Serological survey of Toxoplasma gondii infection in a breeding kennel with reproductive disorders.

Autor: Akhtardanesh B; Department of Clinical Sciences, Veterinary Faculty, Shahid Bahonar University, Kerman, Iran. Electronic address: Akhtardanesh@uk.ac.ir., Aghamiri SM; Department of Clinical Sciences, Veterinary Faculty, Shahid Bahonar University, Kerman, Iran., Foolady D; Department of Clinical Sciences, Veterinary Faculty, Shahid Bahonar University, Kerman, Iran., Sadr S; Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran., Ziaali N; Department of Medical Parasitology and Mycology, Afzalipour Medical School, Kerman University of Medical Sciences, Kerman, Iran., Jajarmi M; Department of Pathobiology, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Iran., Shakib H; Department of Clinical Sciences, Veterinary Faculty, Shahid Bahonar University, Kerman, Iran., Khedri J; Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Jazyk: angličtina
Zdroj: Microbial pathogenesis [Microb Pathog] 2024 Oct; Vol. 195, pp. 106848. Date of Electronic Publication: 2024 Aug 14.
DOI: 10.1016/j.micpath.2024.106848
Abstrakt: Introduction: Toxoplasma gondii (T. gondii) infection in dogs is distributed globally. Given the potential impact of T. gondii on human reproductive health and its zoonotic potential, focusing on infected dogs with breeding disorders may provide valuable new insights into the role of toxoplasmosis on reproductive disorders. This study aimed to elucidate the potential role of T. gondii on reproductive disorders by conducting a serosurvey on a kennel with breeding disorders in Kerman, Iran.
Materials and Methods: Purebred dogs with American Kennel Club-certified Pedigrees were randomly selected in both genders from a breeding kennel with a history of reproductive problems such as neonatal deaths, abortion stillbirths, and male infertility. Blood samples were collected from selected dogs, and serosurvey was done with a Toxo-Screen kit using the modified agglutination test (MAT).
Findings: From 46 selected breeding dogs, 20 (43.5 %) were positive in the Toxoplasma MAT test, consisting of 24 samples (52.17 %) with different reproductive disorders and 22 (47.83 %) healthy dogs. However, the presence of reproductive disorder had no significant relationship with seropositivity (p = 0.067). Seroprevalence of toxoplasmosis had no significant relationship with sex (p = 0.28) and age (p = 0.18) in the studied population.
Conclusion: Screening with the standard MAT method reduces the risk of transmitting toxoplasmosis by preventing the entry of infected dogs into the kennel, identifying the infected cases to start specific treatments, optimizing the proper nutritional conditions, and ensuring the hygiene of the environment. Fresh/refrigerated raw meat, unpasteurized milk feeding, rodent infestation of grass-covered dog runs, and the main dry food storage facilities were the primary risk factors in kennels.
Competing Interests: Declaration of competing interest All authors declare that they have no conflicts of interest.
(Copyright © 2024 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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