Parental Report of Indoor Air Pollution Is Associated with Respiratory Morbidities in Bronchopulmonary Dysplasia.

Autor: Rice JL; Division of Pulmonary Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA., Collaco JM; Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, MD. Electronic address: mcollac1@jhmi.edu., Tracy MC; Division of Pediatric Pulmonary, Asthma and Sleep Medicine, Stanford University, Stanford, CA., Sheils CA; Division of Pulmonary Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA., Rhein LM; Neonatal-Perinatal Medicine/Pediatric Pulmonology, University of Massachusetts, Worcester, MA., Popova AP; Pediatric Pulmonology, University of Michigan, Ann Arbor, MI., Moore PE; Pulmonary Medicine, Vanderbilt University and Vanderbilt University Medical Center, Nashville, TN., Miller AN; Division of Neonatology, Nationwide Children's Hospital and Ohio State University, Columbus, OH., Manimtim WM; Division of Neonatology, Children's Mercy-Kansas City and University of Missouri Kansas City School of Medicine, Kansas City, MO., Lai K; Division of Pediatric Pulmonary and Sleep Medicine, University of Utah, Salt Lake City, UT., Kaslow JA; Pulmonary Medicine, Vanderbilt University and Vanderbilt University Medical Center, Nashville, TN., Hayden LP; Division of Pulmonary Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA., Fierro JL; Division of Pulmonary Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA., Bansal M; Pulmonology and Sleep Medicine, Children's Hospital of Los Angeles, Los Angeles, CA., Austin ED; Pulmonary Medicine, Vanderbilt University and Vanderbilt University Medical Center, Nashville, TN., Aoyama B; Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University, Baltimore, MD., Alexiou S; Division of Pulmonary Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA., Akangire G; Division of Neonatology, Children's Mercy-Kansas City and University of Missouri Kansas City School of Medicine, Kansas City, MO., Agarwal A; Division of Pulmonary Medicine, Arkansas Children's Hospital and University of Arkansas for Medical Sciences, Little Rock, AR., Villafranco N; Pulmonary Medicine, Texas Children's Hospital and Baylor College of Medicine, Houston, TX., Siddaiah R; Pediatric Pulmonology, Penn State Health, Hershey, PA., Lagatta JM; Department of Pediatrics, Medical College of Wisconsin Milwaukee, WI., Abul MH; Department of Pediatrics, Brown University School of Medicine, Providence, RI., Cristea AI; Division of Pediatric Pulmonology, Allergy and Sleep Medicine, Riley Children's Hospital and Indiana University, Indianapolis, IN., Baker CD; Section of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO., Abman SH; Section of Pulmonary and Sleep Medicine, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO., McGrath-Morrow SA; Division of Pulmonary Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA.
Jazyk: angličtina
Zdroj: The Journal of pediatrics [J Pediatr] 2024 Dec; Vol. 275, pp. 114241. Date of Electronic Publication: 2024 Aug 14.
DOI: 10.1016/j.jpeds.2024.114241
Abstrakt: Objective: To determine the association between indoor air pollution and respiratory morbidities in children with bronchopulmonary dysplasia (BPD) recruited from the multicenter BPD Collaborative.
Study Design: A cross-sectional study was performed among participants <3 years old in the BPD Collaborative Outpatient Registry. Indoor air pollution was defined as any reported exposure to tobacco or marijuana smoke, electronic cigarette emissions, gas stoves, and/or wood stoves. Clinical data included acute care use and chronic respiratory symptoms in the past 4 weeks.
Results: A total of 1011 participants born at a mean gestational age of 26.4 ± 2.2 weeks were included. Most (66.6%) had severe BPD. More than 40% of participants were exposed to ≥1 source of indoor air pollution. The odds of reporting an emergency department visit (OR, 1.7; 95% CI, 1.18-2.45), antibiotic use (OR, 1.9; 95% CI, 1.12-3.21), or a systemic steroid course (OR, 2.18; 95% CI, 1.24-3.84) were significantly higher in participants reporting exposure to secondhand smoke (SHS) compared with those without SHS exposure. Participants reporting exposure to air pollution (not including SHS) also had a significantly greater odds (OR, 1.48; 95% CI, 1.08-2.03) of antibiotic use as well. Indoor air pollution exposure (including SHS) was not associated with chronic respiratory symptoms or rescue medication use.
Conclusions: Exposure to indoor air pollution, especially SHS, was associated with acute respiratory morbidities, including emergency department visits, antibiotics for respiratory illnesses, and systemic steroid use.
Competing Interests: Declaration of Competing Interest Supported by the NIH (JLR: K23ES029985). All authors disclose that they have no financial interests in the subject of this manuscript.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: