Effects of chemoradiation and tongue exercise on swallow biomechanics and bolus kinematics.

Autor: Schaen-Heacock NE; Department of Communication Sciences and Disorders, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA., Rowe LM; Department of Communication Sciences and Disorders, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA., Ciucci MR; Department of Communication Sciences and Disorders, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA.; Neuroscience Training Program, University of Wisconsin-Madison, Madison, Wisconsin, USA., Russell JA; Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jazyk: angličtina
Zdroj: Head & neck [Head Neck] 2024 Aug 16. Date of Electronic Publication: 2024 Aug 16.
DOI: 10.1002/hed.27899
Abstrakt: Background: Common treatments for head and neck cancer (radiation and chemotherapy) can lead to dysphagia; tongue exercise is a common intervention. This study aimed to assess swallow biomechanics and bolus kinematics using a well-established rat model of radiation or chemoradiation treatment to the tongue base, with or without tongue exercise intervention.
Methods: Pre- and post-treatment videofluoroscopy was conducted on 32 male Sprague-Dawley rats treated with radiation/chemoradiation and exercise/no exercise. Rats in the exercise groups completed a progressive resistance tongue training paradigm. Swallow biomechanics, bolus kinematics, jaw opening, and post-swallow respiration were assessed.
Results: Both treatments impacted outcome measures; the addition of exercise intervention showed benefit for some measures, particularly in rats treated with radiation, vs. chemoradiation.
Conclusions: Radiation and chemoradiation can significantly affect aspects of deglutition; combined treatment may result in worse outcomes. Tongue exercise intervention can mitigate deficits; more intensive intervention may be warranted in proportion to combined treatment.
(© 2024 The Author(s). Head & Neck published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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