Association of reduced peak left atrial strain with supraventricular arrhythmia in adults with congenital heart disease.

Autor: Nussbaumer C; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Schwerzmann M; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Elchinova E; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Goulouti E; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Tobler D; Department of Cardiology, Basel University Hospital, Basel, Switzerland., Greutmann M; Department of Cardiology, Zurich University Hospital, Zurich, Switzerland., Wustmann K; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Department of Pediatric Cardiology and Congenital Heart Disease, German Heart Center Munich, Munich, Germany., Papa A; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Schwitz F; Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. fabienne.schwitz@insel.ch.; Department of Cardiology, Inselspital, Center for Congenital Heart Disease, Bern University Hospital, Freiburgstrasse 18, Bern, 3010, Switzerland. fabienne.schwitz@insel.ch.
Jazyk: angličtina
Zdroj: The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2024 Oct; Vol. 40 (10), pp. 2133-2144. Date of Electronic Publication: 2024 Aug 16.
DOI: 10.1007/s10554-024-03205-9
Abstrakt: Atrial arrhythmias are an important cause of morbidity and mortality in adults with congenital heart disease (ACHD). In acquired heart disease, the left atrial (LA) strain has been shown to predict supraventricular tachyarrhythmias (SVT). This study aimed to investigate whether reduced LA strain is associated with SVT in ACHD patients. This retrospective, single-center cohort study collected baseline clinical and echocardiographic data of 206 ACHD patients (157 left heart defect, 49 right heart defect). Patients with sinus rhythm at baseline and a 5-year follow-up (median age 29, IQR 22-41 years) were included. Diagnosis of sustained SVT was determined from clinical reports during the follow-up period. New or recurrent sustained SVT occurred in 16 patients (7.8%, median follow-up of 6.2 years). Patients who developed SVT were older, more likely to have diastolic dysfunction, and had larger LA dimensions, left ventricular mass, and a lower peak LA longitudinal strain (PALS). Lower PALS was associated with higher risk of SVT in patients with left and right heart defects. Patients in the lowest quartile for PALS had a 15.9-fold higher hazard ratio of SVT (95% confidence interval, 4.5 to 56.0, p < 0.001) in comparison with the top three quartiles. PALS provides information about the occurrence of SVT in the ACHD population. Including measurement of LA strain in the follow-up of these patients may allow to better identify patients at risk of future atrial arrhythmias.
(© 2024. The Author(s).)
Databáze: MEDLINE
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