Comparison between a new transepithelial PRK vs. conventional alcohol-assisted PRK: Corneal densitometry and aberrometry study.

Autor: Aramberri J; Miranza Begitek, Donostia-San Sebastián, Spain.; Miranza Ókular, Vitoria-Gasteiz, Spain., Lauzirika G; Miranza Begitek, Donostia-San Sebastián, Spain.; Miranza Group R&D Department, Spain., Illarramendi I; Miranza Begitek, Donostia-San Sebastián, Spain., Mendicute J; Miranza Begitek, Donostia-San Sebastián, Spain.; Hospital Universitario Donostia, Donostia-San Sebastián, Spain.
Jazyk: angličtina
Zdroj: European journal of ophthalmology [Eur J Ophthalmol] 2024 Aug 15, pp. 11206721241267360. Date of Electronic Publication: 2024 Aug 15.
DOI: 10.1177/11206721241267360
Abstrakt: Purpose: To describe and compare corneal densitometry, subjective refraction, visual acuity, and corneal higher order aberrations (HOA) after corneal refractive surgery using either alcohol-assisted photorefractive keratectomy (aaPRK) or single-step transepithelial PRK (tPRK).
Methods: We conducted a retrospective and observational study. We analyzed 120 right eyes from 120 healthy consecutive myopic patients who underwent aaPRK or tPRK to correct myopia of up to 6 diopters and astigmatism of up to 2 diopters. The WaveLight EX500 excimer laser (Alcon Laboratories, Inc.) was used in all cases. Visual acuity, subjective refraction, and Pentacam AXL® measurements were performed at the preoperative visit and at 6-months follow-up visit. Pentacam AXL® software was used to assess corneal optical density in various annuli for different corneal depths and anterior corneal HOA (6 mm area of analysis).
Results: Preoperative spherical equivalent values were similar between groups preoperatively (-3.07 ± 1.52 and -3.38 ± 1.46 in the aaPRK and tPRK groups, respectively). There were no statistically significant differences in visual acuity and postoperative refraction between groups. Postoperative corneal densitometry did not show statistically significant differences in any of the areas studied and both surgical procedures obtained similar results. However, analysis of HOA showed statistically significant differences between the techniques (1.42 ± 0.39 and 1.80 ± 0.62 for the aaPRK and tPRK groups, respectively; p  = 0.000).
Conclusions: Both aaPRK and single-step tPRK gave comparable visual, refractive, and corneal density outcomes. Some differences were observed in HOA but were not clinically relevant.
Competing Interests: Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE