Rare Causes of Gastrointestinal Hemorrhage: A Case Series of Adult Duodenal and Jejunal Gastric Heterotopia.

Autor:	Matli VVK; Internal Medicine, Christus Highland Medical Center, Shreveport, USA., Kirkikis J; Gastroenterology and Hepatology, Christus Highland Medical Center, Shreveport, USA., Wellman G; Gastrointestinal and Liver Pathology, The Delta Pathology Group, Shreveport, USA., Hadley D; Gastroenterology and Hepatology, Christus Highland Medical Center, Shreveport, USA., Dies RM; Internal Medicine, Louisiana State University (LSU) Health New Orleans, New Orleans, USA., Dies DF; Gastroenterology and Hepatology, Christus Highland Medical Center, Shreveport, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jul 15; Vol. 16 (7), pp. e64604. Date of Electronic Publication: 2024 Jul 15 (Print Publication: 2024).
DOI:	10.7759/cureus.64604
Abstrakt:	Gastric heterotopia (GH) is a rare cause of gastrointestinal bleeding. GH of the small bowel is rare, and the duodenum is more commonly involved than the jejunum. Here, we present five cases of GH involving the duodenum and jejunum, with presentations including gastrointestinal bleeding, symptomatic anemia, and no symptoms. A 63-year-old man presented with melenic stools but could not identify an obvious bleeding source during endoscopy. He was ultimately diagnosed with jejunal GH. A 70-year-old woman with melena and severe anemia had a duodenal bulb mass detected during endoscopy, which was histopathologically diagnosed as GH. A 54-year-old woman experienced nausea, vomiting, and dysphagia. Endoscopy revealed esophagitis and a duodenal GH without malignancy. A 69-year-old woman incidentally had duodenal GH during evaluation for a lung mass, which was later diagnosed as an aggressive neuroendocrine tumor. The fifth patient was an 83-year-old woman who was admitted for profound significant anemia. Upper endoscopy showed a round, 0.3 cm ulcer in the duodenum and a duodenal polyp with a tiny ulcer, and her histopathology was consistent with GH. The exact mechanism of the action of GH remains unknown. Its clinical presentation is variable, gastrointestinal bleeding is rare, and diagnosis is based on histopathology only. Our case series emphasizes the need to include GH in the differential diagnosis of patients presenting with gastrointestinal bleeding, with or without other associated symptoms. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Matli et al.)
Databáze:	MEDLINE
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