Syncope in the Emergency Department: A Case Report of a Rare Presentation of Favism.

Autor: Couvreur C; Emergency Medicine, CHU (Centre Hospitalier Universitaire) UCLouvain (Université Catholique de Louvain) Namur - Godinne, Godinne, BEL., Mitchell J; Anesthesiology, CHU (Centre Hospitalier Universitaire) UCLouvain (Université Catholique de Louvain) Namur - Godinne, Godinne, BEL., Forget P; Anesthesiology, University of Aberdeen, Aberdeen, GBR., Thonon H; Emergency Medicine, CHU (Centre Hospitalier Universitaire) UCLouvain (Université Catholique de Louvain) Namur - Godinne, Godinne, BEL.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Jul 15; Vol. 16 (7), pp. e64592. Date of Electronic Publication: 2024 Jul 15 (Print Publication: 2024).
DOI: 10.7759/cureus.64592
Abstrakt: Consumption of fava beans in a patient with glucose-6-phosphate dehydrogenase (G6PD) deficiency, also called favism, can lead to a haemolytic crisis. We report the case of a 69-year-old patient of Iranian origin admitted to the emergency department following syncope. The patient's comprehensive interview and blood analysis revealed that the patient presented a haemolytic crisis triggered by fava beans consumption, due to previously undiagnosed G6PD deficiency. The pathophysiology of favism is complex and clinical presentations of G6PD deficiency are numerous due to multiple genetic variants. Indirect signs, such as the presence of methemoglobinaemia and hemighosts on the blood smear, can aid in the diagnosis. This case highlights the importance of considering G6PD deficiency as a potential diagnosis in case of haemolytic crisis, even in elderly patients.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Couvreur et al.)
Databáze: MEDLINE