Confronting the challenge: a regional perspective by the Latin American pediatric infectious diseases society (SLIPE) expert group on respiratory syncytial virus-tackling the burden of disease and implementing preventive solutions.

Autor:	Debbag R; Latin-American Vaccinology Society, Buenos Aires, Argentina., Ávila-Agüero ML; Pediatric Infectious Diseases Division, Hospital Nacional de Roberto Niños 'Dr. Carlos Sáenz Herrera', Caja Costarricense de Seguro Social (CCSS), San José, Costa Rica.; Center for Infectious Disease Modeling and Analysis (CIDMA), Yale University, New Haven, CT, United States., Brea J; Facultad de Ciencias de La Salud del, Instituto Tecnológico de Santo Domingo, Santo Domingo, Dominican Republic., Brenes-Chacon H; Pediatric Infectious Diseases Division, Hospital Nacional de Roberto Niños 'Dr. Carlos Sáenz Herrera', Caja Costarricense de Seguro Social (CCSS), San José, Costa Rica., Colomé M; Department of Epidemiology and Public Health, Hospital Pediátrico Dr. Hugo Mendoza, Santiago Domingo, Dominican Republic., de Antonio R; Executive and Scientific Director, Centro de Vacunación de Investigación (CEVAXIN), Panama City, Panama., Díaz-Díaz A; Pediatric Infectious Diseases Department, Hospital Pablo Tobón Uribe and Hospital General de Medellín, Medellín, Colombia., Falleiros-Arlant LH; Departamento de Salud del Niño de la Facultad de Medicina de la, Universidad Metropolitana de Santos, São Paulo, Brazil., Fernández G; Department of Pediatrics and Infantil Surgery Oriente, Hospital Luis Calvo Mackenna and Faculty of Medicine, Universidad de Chile, Santiago, Chile., Gentile A; Epidemiology Department, Hospital de Niños R. Gutiérrez, Universidad de Buenos Aires, Buenos Aires, Argentina., Gutiérrez IF; Pediatric Infectious Diseases Department, Clinical Infantil Santa Maria del Lago, Bogota, Colombia., Jarovsky D; Faculdade de Ciências Médicas da Santa Casa de São Paulo, Pediatric Society at São Paulo, São Paulo, Brazil., Del Valle Juárez M; Epidemiology Department, Hospital de Niños R. Gutiérrez, Universidad de Buenos Aires, Buenos Aires, Argentina., López-Medina E; Centro de Estudios en Infectología Pediátrica CEIP, Department of Pediatrics, Universidad del Valle, Clínica Imbanaco, and Grupo Quironsalud, Cali, Colombia., Mascareñas A; Department of Pediatric Infectious Diseases, Hospital Universitario 'José E. Gonzalez', Universidad Autónoma De Nuevo León, Nuevo Leon, México., Ospina-Henao S; Faculty of Medicine, Universidad de Ciencias Médicas, UCIMED, San José, Costa Rica., Safadi MA; Department of Pediatrics, Faculda de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil., Sáez-Llorens X; Clinical Research, Hospital del Niño Dr. José Renán Esquivel and Senacyt (SNI) y Cevaxin, Panama City, Panama., Soriano-Fallas A; Pediatric Infectious Diseases Division, Hospital Nacional de Roberto Niños 'Dr. Carlos Sáenz Herrera', Caja Costarricense de Seguro Social (CCSS), San José, Costa Rica., Torres JP; Department of Pediatrics and Children Surgery, Universidad de Chile, Santiago, Chile., Torres-Martínez CN; Department of Pediatrics, Universidad El Bosque, Cafettor Médica SAS, Bogotá, Colombia., Beltrán-Arroyave C; Clínica El Rosario and Clínica del Prado, Faculty of Medicine, Universidad de Antioquia, Medellín, Colombia.
Jazyk:	angličtina
Zdroj:	Frontiers in pediatrics [Front Pediatr] 2024 Jul 31; Vol. 12, pp. 1386082. Date of Electronic Publication: 2024 Jul 31 (Print Publication: 2024).
DOI:	10.3389/fped.2024.1386082
Abstrakt:	Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infections in children around the world. The post-pandemic era has resulted in a notable increase in reported cases of RSV infections, co-circulation of other respiratory viruses, shifts in epidemiology, altered respiratory season timing, and increased healthcare demand. Low- and middle-income countries are responsible for the highest burden of RSV disease, contributing significantly to health expenses during respiratory seasons and RSV-associated mortality in children. Until recently, supportive measures were the only intervention to treat or prevent RSV-infection, since preventive strategies like palivizumab are limited for high-risk populations. Advances in new available strategies, such as long-acting monoclonal antibodies during the neonatal period and vaccination of pregnant women, are now a reality. As the Regional Expert Group of the Latin American Pediatric Infectious Diseases Society (SLIPE), we sought to evaluate the burden of RSV infection in Latin America and the Caribbean (LAC) region, analyze current strategies to prevent RSV infection in children, and provide recommendations for implementing new strategies for preventing RSV infection in children in LAC region. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (© 2024 Debbag, Ávila-Agüero, Brea, Brenes-Chacon, Colomé, de Antonio, Díaz-Díaz, Falleiros-Arlant, Fernández, Gentile, Gutiérrez, Jarovsky, del Valle Juárez, López-Medina, Mascareñas, Ospina-Henao, Safadi, Sáez-Llorens, Soriano-Fallas, Torres, Torres-Martínez and Beltrán-Arroyave.)
Databáze:	MEDLINE
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