| Autor: |
Valenzuela PL; Physical Activity and Health Research Group ('PaHerg'), Research Institute of Hospital 12 de Octubre ('imas12'), Madrid, Spain.; Department of Systems Biology, University of Alcalá, Madrid, Spain., Sitko S; Department of Physiatry and Nursery, University of Zaragoza, Zaragoza, Spain., Pitsiladis Y; International Federation of Sports Medicine (FIMS), Lausanne, Switzerland.; Department of Sport, Physical Education, and Health, Hong Kong Baptist University, Kowloon Tong, Hong Kong. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2024 Oct 01; Vol. 137 (4), pp. 1068-1070. Date of Electronic Publication: 2024 Aug 15. |
| DOI: |
10.1152/japplphysiol.00422.2024 |
| Abstrakt: |
The effects of some widely abused doping substances such as anabolic androgenic steroids (AAS) on performance are well documented, particularly in the short term, and the use of these substances is banned by various sporting authorities, with athletes sanctioned from competing for up to 4 years. However, controversy exists on whether residual physiological effects of some doping practices could persist even years after discontinuation, granting unfair advantages to athletes long after sanctions have been served. Particularly, in support of the so-called muscle memory theory, growing evidence in both animals and humans suggests that AAS administration could exert long-term effects at the muscle level, notably a higher number of myonuclei. This effect could enhance retraining/muscle remodeling capacity long after AAS cessation, thus supposing an advantage for doped athletes even +4 years after doping practices have been discontinued. If confirmed, the persistence of physiological improvements resulting from past doping practices raises serious ethical concerns in the sports field and opens the door to lifelong sanctions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
