Prevalence of hepatitis A and E viruses in wastewater in Asian countries.

Autor: Raya S; Department of Engineering, University of Yamanashi, 4-3-11 Takeda, Kofu, Yamanashi 400-8511, Japan., Tandukar S; Organization for Public Health and Environment Management, Lalitpur, Nepal., Kattel HP; Department of Microbiology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal., Sharma S; Department of Microbiology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal. Electronic address: drsangita_sharma@iom.edu.np., Sangsanont J; Department of Environmental Science, Chulalongkorn University, Phayathai Road, Pathumwan, Bangkok 10330, Thailand; Water Science and Technology for Sustainable Environmental Research Unit, Chulalongkorn University, Bangkok 10330, Thailand. Electronic address: jatuwat.s@chula.ac.th., Sirikanchana K; Research Laboratory of Biotechnology, Chulabhorn Research Institute, 54 Kamphaeng Phet 6 Rd., Talat Bang Khen, Lak Si, Bangkok 10210, Thailand; Center of Excellence on Environmental Health and Toxicology (EHT), OPS, MHESI, Bangkok 10400, Thailand. Electronic address: kwanrawee@cri.or.th., Ngo HTT; Faculty of Biotechnology, Chemistry and Environmental Engineering, Phenikaa University, Yen Nghia, Ha Dong, Hanoi 12116, Viet Nam; Environmental Chemistry and Ecotoxicology Lab, Phenikaa University, Yen Nghia Ward - Ha Dong District, Hanoi 12116, Viet Nam. Electronic address: huong.ngothithuy@phenikaa-uni.edu.vn., Inson JGM; Department of Biology, De La Salle University, 2401 Taft Avenue, Manila 1004, Philippines; Environmental Biomonitoring Research Unit, Center for Natural Sciences and Environmental Research, De La Salle University, Manila 1004, Philippines. Electronic address: jessamine.inson@dlsu.edu.ph., Enriquez MLD; Department of Biology, De La Salle University, 2401 Taft Avenue, Manila 1004, Philippines; Environmental Biomonitoring Research Unit, Center for Natural Sciences and Environmental Research, De La Salle University, Manila 1004, Philippines. Electronic address: ma.luisa.enriquez@dlsu.edu.ph., Alam ZF; Department of Biology, De La Salle University, 2401 Taft Avenue, Manila 1004, Philippines; Environmental Biomonitoring Research Unit, Center for Natural Sciences and Environmental Research, De La Salle University, Manila 1004, Philippines. Electronic address: zeba.alam@dlsu.edu.ph., Setiyawan AS; Department of Environmental Engineering, Institut Teknologi Bandung, Jl. Ganesha No. 10, Bandung 40132, Indonesia; Faculty of Civil and Environmental Engineering, Institut Teknologi Bandung, Jl. Ganesa No. 10, Bandung 40132, Indonesia. Electronic address: ahmad_setiyawan@itb.ac.id., Setiadi T; Department of Chemical Engineering, Institut Teknologi Bandung, Jl. Ganesa 10, Bandung 40132, Indonesia. Electronic address: tjandra.setiadi@itb.ac.id., Haramoto E; Interdisciplinary Center for River Basin Environment, University of Yamanashi, 4-3-11 Takeda, Kofu, Yamanashi 400-8511, Japan. Electronic address: eharamoto@yamanashi.ac.jp.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2024 Nov 15; Vol. 951, pp. 175473. Date of Electronic Publication: 2024 Aug 12.
DOI: 10.1016/j.scitotenv.2024.175473
Abstrakt: Hepatitis A and E viruses (HAV and HEV, respectively) remain a significant global health concern despite advancements in healthcare and vaccination programs. Regular monitoring and vaccine efficacy of HAV are still lacking in different countries. This study aimed to investigate HAV and HEV prevalence in developed, developing, and least-developed Asian countries using wastewater as a surveillance tool. A total of 232 untreated wastewater samples were collected from six wastewater treatment plants, a sewage treatment plant, or an open drainage in six countries [Nepal (n = 51), Indonesia (n = 37), Thailand (n = 30), Vietnam (n = 27), the Philippines (n = 17), and Japan (n = 70)] between April and October 2022. Viruses in wastewater were concentrated by simple centrifugation or polyethylene glycol precipitation method, followed by viral RNA extraction and reverse transcription-quantitative polymerase chain reaction. HAV and HEV RNA were detected in the samples from Nepal (51 % for HAV and 2 % for HEV), Thailand (3 % for both viruses), and Japan (1 % for HAV and 24 % for HEV). Only HAV RNA was found in 11 % of the samples in Indonesia, whereas only HEV RNA was detected in Vietnam and the Philippines, with a positive ratio of 15 % and 12 %, respectively. These results highlighted the geographic variability in HAV and HEV prevalence, underscoring the need for localized public health strategies to address specific viral hepatitis challenges in each country.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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