CNGC15 and DMI1 ion channel gating in nuclear calcium signaling: opening new questions and closing controversies.

Autor:	Jacott CN; Department of Microbiology, University of Seville, Seville, Spain., Del Cerro P; Department of Microbiology, University of Seville, Seville, Spain.
Jazyk:	angličtina
Zdroj:	Journal of experimental botany [J Exp Bot] 2024 Dec 04; Vol. 75 (22), pp. 6998-7005.
DOI:	10.1093/jxb/erae352
Abstrakt:	Nuclear calcium (Ca2+) signaling is crucial for symbiotic interactions between legumes and beneficial microbes, such as rhizobia and arbuscular mycorrhizal fungi. The ion channels DMI1 and CNGC15 are key to generating repetitive nuclear Ca2+ oscillations. Despite more than 20 years of research on symbiotic nuclear Ca2+ spiking, important questions remain, including the exact function of the DMI1 channel. This review highlights recent developments that have filled knowledge gaps regarding the regulation of CNGC15 and its interplay with DMI1. We also explore new insights into the evolutionary conservation of DMI1-induced symbiotic nuclear Ca2+ oscillations and the roles of CNGC15 and DMI1 beyond symbiosis, such as in nitrate signaling, and discuss new questions this raises. As we delve deeper into the regulatory mechanisms and evolutionary history of these ion channels, we move closer to fully understanding the roles of nuclear Ca2+ signaling in plant life. (© The Author(s) 2024. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
Databáze:	MEDLINE
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