Wound healing after intracutaneous vs. staple-assisted skin closure in lumbar, non-instrumented spine surgery: a multicenter prospective randomized trial.

Autor: Romagna A; Department of Neurosurgery, München Klinik Bogenhausen, Englschalkinger Str. 77, 81925, Munich, Germany. alexander.romagna@muenchen-klinik.de.; Department of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria. alexander.romagna@muenchen-klinik.de., Lehmberg J; Department of Neurosurgery, München Klinik Bogenhausen, Englschalkinger Str. 77, 81925, Munich, Germany., Meier M; Department of Neurosurgery, München Klinik Bogenhausen, Englschalkinger Str. 77, 81925, Munich, Germany., Stelzer M; Department of Neurosurgery, München Klinik Bogenhausen, Englschalkinger Str. 77, 81925, Munich, Germany., Rezai A; Department of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria., Anton JV; Department of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria., Eckert A; Department of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria., Griessenauer CJ; Department of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria., Bonk MN; Department of Neurosurgery, University Hospital Augsburg, Augsburg, Germany., Sommer B; Department of Neurosurgery, University Hospital Augsburg, Augsburg, Germany., Shiban E; Department of Neurosurgery, University Hospital Augsburg, Augsburg, Germany.; Department of Neurosurgery, Lausitz University Hospital, Cottbus, Germany., Blume C; Department of Neurosurgery, RWTH Aachen University, Aachen, Germany., Geroldinger M; Team Biostatistics and Big Medical Data, IDA Lab Salzburg, Paracelsus Medical University, Salzburg, Austria.; Research Programme Biomedical Data Science, Paracelsus Medical University, Salzburg, Austria., Schwartz C; Department of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria.
Jazyk: angličtina
Zdroj: Acta neurochirurgica [Acta Neurochir (Wien)] 2024 Aug 13; Vol. 166 (1), pp. 336. Date of Electronic Publication: 2024 Aug 13.
DOI: 10.1007/s00701-024-06227-3
Abstrakt: Purpose: Superficial surgical site infection (SSSI) is a prominent problem in spine surgery. Intracutaneous sutures and staple-assisted closure are two widely used surgical techniques for skin closure. Yet, their comparative impact on wound healing and infection rates is underexplored. Our goal was to address this gap and compare wound healing between these two techniques.
Methods: This study was a multicenter international prospective randomized trial. Patient data were prospectively collected at three large academic centers, patients who underwent non-instrumented lumbar primary spine surgery were included. Patients were intraoperatively randomized to either intracutaneous suture or staple-assisted closure cohorts. The primary endpoint was SSSI within 30 days after surgery according to the wound infection Centers for Disease Control and Prevention (CDC) classification system.
Results: Of 207 patients, 110 were randomized to intracutaneous sutures and 97 to staple-assisted closure. Both groups were homogenous with respect to epidemiological as well as surgical parameters. Two patients (one of each group) suffered from an A1 wound infection at the 30-day follow up. Median skin closure time was faster in the staple-assisted closure group (198 s vs. 13 s, p < 0,001).
Conclusion: This study showed an overall low superficial surgical site infection rate in both patient cohorts in primary non instrumented spine surgery.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)
Databáze: MEDLINE
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