Digital solutions in paediatric sepsis: current state, challenges, and opportunities to improve care around the world.

Autor:	Sanchez-Pinto LN; Department of Pediatrics, Northwestern University Feinberg School of Medicine and Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA. Electronic address: lsanchezpinto@luriechildrens.org., Del Pilar Arias López M; Children's Hospital Ricardo Gutierrez, SATI-Q Program, Buenos Aires, Argentina., Scott H; Department of Pediatrics, University of Colorado-Denver and Children's Hospital Colorado, Aurora, CO, USA., Gibbons K; Children's Intensive Care Research Program, Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia., Moor M; Department of Computer Science, Stanford University, Stanford, CA, USA., Watson RS; Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, WA, USA., Wiens MO; Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada; World Alliance for Lung and Intensive Care Medicine in Uganda, Kampala, Uganda., Schlapbach LJ; Children's Intensive Care Research Program, Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia; Department of Intensive Care and Neonatology, University Children's Hospital Zurich, University of Zurich, Zurich, Switzerland., Bennett TD; Department of Pediatrics, University of Colorado-Denver and Children's Hospital Colorado, Aurora, CO, USA.
Jazyk:	angličtina
Zdroj:	The Lancet. Digital health [Lancet Digit Health] 2024 Sep; Vol. 6 (9), pp. e651-e661. Date of Electronic Publication: 2024 Aug 12.
DOI:	10.1016/S2589-7500(24)00141-9
Abstrakt:	The digitisation of health care is offering the promise of transforming the management of paediatric sepsis, which is a major source of morbidity and mortality in children worldwide. Digital technology is already making an impact in paediatric sepsis, but is almost exclusively benefiting patients in high-resource health-care settings. However, digital tools can be highly scalable and cost-effective, and-with the right planning-have the potential to reduce global health disparities. Novel digital solutions, from wearable devices and mobile apps, to electronic health record-embedded decision support tools, have an unprecedented opportunity to transform paediatric sepsis research and care. In this Series paper, we describe the current state of digital solutions in paediatric sepsis around the world, the advances in digital technology that are enabling the development of novel applications, and the potential effect of advances in artificial intelligence in paediatric sepsis research and clinical care. Competing Interests: Declaration of interests RSW served on the data safety monitoring board of the GRACE trial (granulocyte-macrophage colony-stimulating factor for reversal of immunoparalysis in pediatric sepsis-induced multiple organ dysfunction syndrome), chairs the data safety monitoring board of the PRECISE study (personalized immunomodulation in pediatric sepsis-induced multiple organ dysfunction syndrome), and is a co-investigator on the SHIPSS trial (stress hydrocortisone for pediatric septic shock; R01HD096901). LNS-P has stock options in Celldom, Saccharo, Allyx Therapeutics, and InnoSIGN, which are companies focused on diagnostic and therapeutic approaches to cancer and Alzheimer's disease, not sepsis. HS has received support for travel to meetings related to sepsis quality improvement from the Children's Hospital Association, and travel support from the Society of Critical Care Medicine. RSW declares travel support from the Society of Critical Care Medicine, and is co-chair (unpaid) of the Pediatric Sepsis Definitions Task Force for the Society of Critical Care Medicine. LNS-P, HS, LJS, and TDB are members (unpaid) of the Pediatric Sepsis Definitions Task Force for the Society of Critical Care Medicine. All other authors declare no competing interests. (Copyright © 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license.)
Databáze:	MEDLINE
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