Can a Carbonated Lemon Drink Reduce Extracardiac Activity in Myocardial Perfusion Imaging?

Autor:	Al-Somali N; Nuclear Medicine Section, Department of Radiology, King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia; noary.alsomali@gmail.com., El-Zeftawy H; Nuclear Medicine Section, Department of Radiology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; and., Al-Qurashi S; Nuclear Medicine Section, Department of Radiology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; and., Mishah N; Nuclear Medicine Section, Department of Radiology, King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia., Catipay JN; Nuclear Medicine Section, Department of Radiology, King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia., Albalbeesi L; Nuclear Medicine Section, Department of Radiology, King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia., Al-Eatany Y; Nuclear Medicine Section, Department of Radiology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; and., Al-Alahmadii N; Nuclear Medicine Section, Department of Radiology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; and., Alghamdi A; Nuclear Medicine Section, Department of Radiology, King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia., Osman AA; Faculty of Public Health and Health Informatics, Umm Al-Qura University, Mecca, Saudi Arabia., Batawil N; Nuclear Medicine Section, Department of Radiology, King Abdul-Aziz University Hospital, Jeddah, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Journal of nuclear medicine technology [J Nucl Med Technol] 2024 Sep 05; Vol. 52 (3), pp. 239-246. Date of Electronic Publication: 2024 Sep 05.
DOI:	10.2967/jnmt.124.267965
Abstrakt:	Myocardial perfusion imaging (MPI) provides physiologic and functional information about the heart muscle and its blood flow. Extracardiac radioactivity can interfere with visualization of the inferior wall of the myocardium, leading to poor-quality images, difficulties in interpretation, and delays in routine practice. This study aimed to identify the efficiency of having the patient consume a carbonated lemon drink to minimize the extracardiac radioactivity of 99m Tc-sestamibi in comparison to 99m Tc-tetrofosmin during MPI. Methods: This was a retrospective study that recruited 158 patients with known or suspected coronary artery disease referred to undergo 99m Tc-sestamibi or 99m Tc-tetrofosmin rest/stress single-day MPI. The patients were divided into 2 groups of mixed sexes and different ages. The first group comprised 78 patients injected with 99m Tc-sestamibi, and the second group comprised 80 patients injected with 99m Tc-tetrofosmin. For both groups, the patients drank 30 mL of fresh lemon juice diluted with 150 mL of soda water, and then we gave the patients about 100 mL of straight soda water, before imaging for both the rest and the stress phases. Results: Generally, in both groups, the 99m Tc-tetrofosmin produced a good-quality image in comparison with the 99m Tc-sestamibi. The mean rank of the total score for 99m Tc-tetrofosmin (62.75) was less than that for 99m Tc-sestamibi (96.68), and this difference was highly statistically significant ( P = 0.000). There were statistically significant differences in the ratios and mean ranks for both groups in favor of 99m Tc-tetrofosmin in patients having coronary artery disease. Conclusion: The use of a carbonated lemon drink minimizes extracardiac activity from both 99m Tc-labeled MPI radiopharmaceuticals. This finding was more statistically significant for 99m Tc-tetrofosmin MPI, providing better image quality and earlier imaging in both the rest and the stress phases because of faster hepatobiliary clearance. (© 2024 by the Society of Nuclear Medicine and Molecular Imaging.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu