Primate hibernation: The past, present, and promise of captive dwarf lemurs.

Autor: Blanco MB; Department of Biology, Duke University, Durham, North Carolina, USA.; Duke Lemur Center, Duke University, Durham, North Carolina, USA., Greene LK; Department of Biology, Duke University, Durham, North Carolina, USA.; Duke Lemur Center, Duke University, Durham, North Carolina, USA., Welser KH; Duke Lemur Center, Duke University, Durham, North Carolina, USA., Ehmke EE; Duke Lemur Center, Duke University, Durham, North Carolina, USA., Yoder AD; Department of Biology, Duke University, Durham, North Carolina, USA., Klopfer PH; Department of Biology, Duke University, Durham, North Carolina, USA.
Jazyk: angličtina
Zdroj: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2024 Oct; Vol. 1540 (1), pp. 178-190. Date of Electronic Publication: 2024 Aug 13.
DOI: 10.1111/nyas.15206
Abstrakt: The dwarf lemurs (Cheirogaleus spp.) of Madagascar are the only obligate hibernators among primates. Despite century-old field accounts of seasonal lethargy, and more recent evidence of hibernation in the western fat-tailed dwarf lemur (Cheirogaleus medius), inducing hibernation in captivity remained elusive for decades. This included the Duke Lemur Center (DLC), which maintains fat-tailed dwarf lemurs and has produced sporadic research on reproduction and metabolism. With cumulative knowledge from the field, a newly robust colony, and better infrastructure, we recently induced hibernation in DLC dwarf lemurs. We describe two follow-up experiments in subsequent years. First, we show that dwarf lemurs under stable cold conditions (13°C) with available food continued to eat daily, expressed shallower and shorter torpor bouts, and had a modified gut microbiome compared to peers without food. Second, we demonstrate that dwarf lemurs under fluctuating temperatures (12-30°C) can passively rewarm daily, which was associated with altered patterns of fat depletion and reduced oxidative stress. Despite the limitations of working with endangered primates, we highlight the promise of studying hibernation in captive dwarf lemurs. Follow-up studies on genomics and epigenetics, metabolism, and endocrinology could have relevance across multidisciplinary fields, from biomedicine to evolutionary biology, and conservation.
(© 2024 The New York Academy of Sciences.)
Databáze: MEDLINE
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