Bipolar disorder and oxidative stress: A bibliometric perspective.

Autor: Gui Z; Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, University of Macau, Macao, China.; Centre for Cognitive and Brain Sciences, University of Macau, Macao, China., Zhang Q; Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China., Sha S; Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China., Li XH; Beijing Huilongguan Hospital, Peking University Huilongguan Clinical Medical School, Beijing, China., Su Z; School of Public Health, Southeast University, Nanjing, China., Cheung T; School of Nursing, Hong Kong Polytechnic University, Hong Kong, China., Cui XL; Department of Business Administration, Hong Kong Shue Yan University, Hong Kong, China., Ungvari GS; Section of Psychiatry, University of Notre Dame Australia, Fremantle, Australia.; Division of Psychiatry, School of Medicine, University of Western Australia, Perth, Australia., Wong KK; Faculty of Arts and Humanities, University of Macau, Macao, China., Ng CH; Department of Psychiatry, The Melbourne Clinic and St Vincent's Hospital, University of Melbourne, Richmond, VIC, Australia., Yuan F; Beijing Key Laboratory of Mental Disorders, National Clinical Research Center for Mental Disorders & National Center for Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China., Xiang YT; Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, University of Macau, Macao, China.; Centre for Cognitive and Brain Sciences, University of Macau, Macao, China.
Jazyk: angličtina
Zdroj: Asia-Pacific psychiatry : official journal of the Pacific Rim College of Psychiatrists [Asia Pac Psychiatry] 2024 Sep; Vol. 16 (3), pp. e12564.
DOI: 10.1111/appy.12564
Abstrakt: Objective: Accumulating evidence indicates that oxidative stress and the disruption of antioxidant defenses play an important role in the neurobiology of bipolar disorder (BD). Studies have found that increased oxidative stress may be associated with cell apoptosis and neuronal damage in BD patients. Hence, this study explored the research field related to BD and oxidative stress from a bibliometrics perspective.
Methods: Literature search and relevant data retrieval based on the Web of Sciences Core Collection (WoSCC). R software (version 4.2.2), VOSviewer software (version 1.6.18), and CiteSpace (version 6.1.6) were used in this bibliometric analysis.
Results: A total of 2081 publications related to BD and oxidative stress were published between 1986 and 2024. Bipolar Disorders was the journal that had the most publications in this area (72; 3.46%; IF = 5.9), while the United States (1285; 61.7%) and the University of Toronto (377; 18.1%) were the most productive country and institution, respectively. Apart from "oxidative stress" and "bipolar disorder," the most frequently used keywords were "schizophrenia," "prefrontal cortex," and "nitric oxide."
Conclusions: The growing number of publications related to BD and oxidative stress in recent years highlights the importance of this research field. Hot topics in research related to BD and oxidative stress included animal experiments and molecular mechanisms, psychiatric-related inflammation and biomarkers, neurodegenerative diseases, and metabolism. Furthermore, the biological mechanisms of BD, particularly biomarkers and inflammation, may be the emerging research priority area in the future.
(© 2024 The Author(s). Asia‐Pacific Psychiatry published by John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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