Aesthetic Radiofrequency Associated with Rosmarinus officinalis Supplementation is Safe and Reduces Oxidative Stress in Women: Randomized, and Double-Blind Clinical Trial.

Autor:	Tremêa GTF; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., Kleibert KRU; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., Krause LS; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., Fell APW; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., Scapini AR; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., Marschall KW; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., Baiotto CS; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., da Silva MHT; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., da Silva JAG; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil., Colet CF; Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUÍ, Ijui, Brazil.
Jazyk:	angličtina
Zdroj:	Journal of evidence-based integrative medicine [J Evid Based Integr Med] 2024 Jan-Dec; Vol. 29, pp. 2515690X241246293.
DOI:	10.1177/2515690X241246293
Abstrakt:	The objective were to evaluate the effects of supplementation of standardized dry extract of Rosmarinus officinalis (RO) and the application of aesthetic radiofrequency on the oxidative stress markers catalase (CAT), superoxide dismutase (SOD), non-protein thiols (NP-SH), and thiobarbituric acid reactive species (TBARS) and the biochemical markers triglycerides, total cholesterol, high density lipoprotein (HDL) cholesterol, glutamic-oxaloacetic transaminase (TGO/AST), pyruvic-glutamic transaminase (TGP/ALT), gamma glutamyl transpeptidase (gamma-GT), and creatinine. This study included 32 women received the aesthetic therapy to reduce localized fat. They were divided into the control group (n = 8) receiving placebo capsules and the intervention group (n = 24) subdivided into Group A, B, and C, each with eight members receiving supplementation with 100, 500, and 1000 mg/day of standardized dry extract of RO, respectively. The Universal Trial Number (UTN) - U1111-1274-6255. Supplementation with RO (500 mg/day) demonstrated a reduction in oxidative stress (quantified with through a significant increase in NP-SH and a reduction in SOD and CAT enzymes). The radiofrequency aesthetic treatment did not promote an increase in oxidative stress; however, it caused significant changes in total cholesterol, HDL cholesterol, and creatinine. RO is a plant with antioxidant effects and its oral consumption is safe in selected women subjects in hepatic and renal markers. Competing Interests: Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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