Recent cervical cancer incidence, stage at diagnosis, and mortality trends in Puerto Rico, 2001-2019.

Autor: Ortiz AP; University of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico. ana.ortiz7@upr.edu.; Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico. ana.ortiz7@upr.edu., Torres-Cintrón CR; Comprehensive Cancer Center, Puerto Rico Central Cancer Registry, Cancer Control and Population Sciences Division, University of Puerto Rico, San Juan, Puerto Rico., Santiago-Rodríguez EJ; University of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico., Ramos-Cartagena JM; University of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico., Suárez-Ramos T; Comprehensive Cancer Center, Puerto Rico Central Cancer Registry, Cancer Control and Population Sciences Division, University of Puerto Rico, San Juan, Puerto Rico., Damgacioglu H; Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA., Colón-López V; University of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico., Ortiz-Ortiz KJ; University of Puerto Rico Comprehensive Cancer Center, P.O. Box 363027, 00936-3027, San Juan, Puerto Rico.; Graduate School of Public Health, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico.; Comprehensive Cancer Center, Puerto Rico Central Cancer Registry, Cancer Control and Population Sciences Division, University of Puerto Rico, San Juan, Puerto Rico., Deshmukh AA; Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA.; Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, USA.
Jazyk: angličtina
Zdroj: BMC medicine [BMC Med] 2024 Aug 13; Vol. 22 (1), pp. 327. Date of Electronic Publication: 2024 Aug 13.
DOI: 10.1186/s12916-024-03535-4
Abstrakt: Background: Cervical cancer incidence is rising in Puerto Rico (PR). Whether the increase is real or reflective of increased diagnostic scrutiny remains unclear.
Methods: Using data from the PR Central Cancer Registry for 2001-2019, we estimated trends of hysterectomy-corrected cervical cancer incidence and mortality rates, overall, and by stage at diagnosis and age.
Results: Overall, cervical cancer incidence (per 100,000) increased 1.6%/year (95% CI, -0.5% to 3.8%) from 12.5 to 15.3, with a prominent increase in distant-stage disease (4.5%/year [95% CI, 1.6% to 8.0%]), particularly among screening age eligible (25-64-year-old) women (5.8%/year [95% CI, 2.1% to 10.6%]). Mortality rates in this age-group remained stable during the study period.
Conclusions: Increased occurrence of distant-stage disease among screening-eligible women is troubling and may reflect a real increase. Future research is needed to elucidate the factors underlying these trends. Improved prevention is also an urgent priority to reverse the rising cervical cancer incidence in PR.
(© 2024. The Author(s).)
Databáze: MEDLINE
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