Predictive Ability of Inflammatory Markers on In-Hospital Outcomes in Patients Admitted to Coronary Care Unit (MORCOR-TURK INFLAME).

Autor:	Kümet Ö; Department of Cardiology, Health Sciences University, Van Educational and Research Hospital, Van, Turkey., Özgeyik M; Department of Cardiology, Eskişehir City Hospital, Eskisehir, Turkey., Topuz Ş; Department of Cardiology, Tekirdag Dr. İsmail Fehmi Cumalıoglu City Hospital, Tekirdg, Turkey., Taşcanov MB; Cardiology Department, Harran University Faculty of Medicine, Sanliurfa, Turkey., Dindaş F; Cardiology Department, Uşak University Faculty of Medicine, Usak, Turkey., Şahin İ; Department of Cardiology, Bagcılar Training and Research Hospital, Istanbul, Turkey., Ersoy İ; Cardiology Department, Afyonkarahisar Health Science University, Afyon, Turkey., Tanboğa İH; Cardiology and Biostatistics Department Istanbul Nişantaşı University Faculty of Medicine, Istanbul, Turkey.
Jazyk:	angličtina
Zdroj:	Angiology [Angiology] 2024 Aug 12, pp. 33197241273389. Date of Electronic Publication: 2024 Aug 12.
DOI:	10.1177/00033197241273389
Abstrakt:	We investigated the prognostic implications of the systemic immune-inflammatory index (SII), atherogenic index of plasma (AIP), C-reactive protein/albumin ratio (CAR), neutrophil-lymphocyte ratio (NLR), prognostic nutritional index (PNI), and triglyceride/glucose index (TGI) in the MORtality predictors in the CORonary Care Units in TURKey (MORCOR-TURK) population. This is the largest registry of coronary care unit (CCU) patients in Turkey (3157 patients admitted to CCU in 50 different centers). The study population was divided into two according to in-hospital survival status; 137 patients (4.3%) died in-hospital follow-up. A significant correlation was found between death and SII, CAR, NLR, and PNI but not for AIP and TGI in logistic regression. In Model 1 (combining parameters proven to be risk predictors), the -2 log-likelihood ratio was 888.439, Nagelkerke R 2 was 0.235, and AUC (area under curve) was 0.814 (95% CI: 0.771-0.858). All other models were constructed by adding each inflammatory marker separately to Model 1. Only Model 3 (CAR + Model 1) had a significantly greater AUC than Model 1 (DeLong P = .01). Our study showed that CAR, but not other inflammatory index, is a significant predictor of in-hospital mortality in CCU patients when added to proven risk predictors. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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