Effect of differences in proximal neck angles on biomechanics of abdominal aortic aneurysm based on fluid dynamics.

Autor:	Wang YY; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Chen J; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Luo DY; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Chen H; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Deng ZH; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Chen MZ; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Mi SY; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Xie QQ; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Zou QQ; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Xiong GZ; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China., Bi GS; Department of Vascular Surgery, The Second Affiliated Hospital of University of South China, Hengyang, China.
Jazyk:	angličtina
Zdroj:	Vascular [Vascular] 2024 Aug 12, pp. 17085381241273262. Date of Electronic Publication: 2024 Aug 12.
DOI:	10.1177/17085381241273262
Abstrakt:	Background: This study aimed to analyze the effect of proximal neck angulation on the biomechanical indices of abdominal aortic aneurysms (AAA) and to investigate its impact on the risk of AAA rupture. Methods: CT angiography (CTA) data of patients with AAA from January 2015 to January 2022 were collected. Patients were divided into three groups based on the angle of the proximal neck: Group A (∠β ≤ 30°), Group B (30°<∠β ≤ 60°), and Group C (∠β > 60°). Biomechanical indices related to the rupture risk of AAA were analyzed using computational fluid dynamics modeling (CFD-Post) based on the collected data. Results: Group A showed slight turbulence in the AAA lumen with a mixed laminar flow pattern. Group B had a regular low-speed eddy line characterized by cross-flow dominated by lumen blood flow and turbulence. In Group C, a few turbulent lines appeared at the proximal neck, accompanied by eddy currents in the lumen expansion area following the AAA shape. Significant differences were found in peak wall stress, shear stress, and the maximum blood flow velocity impact among the three groups. The maximum blood flow velocity at the angle of the proximal neck impact indicated the influence of the proximal neck angle on the blood flow state in the lumen. Conclusion: As the angle of the proximal neck increased, it caused stronger eddy currents and turbulent blood flow due to a high-speed area near the neck. The region with the largest diameter in the abdominal aortic aneurysm was prone to the highest stress, indicating a higher risk of rupture. The corner of the proximal neck experienced the greatest shear stress, potentially leading to endothelial injury and further enlargement of the aneurysm. Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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