Multidrug-Resistant Shigellosis as a Sexually Transmitted Infection in Advanced HIV: A Case Report.

Autor:	Bhatia MK; Department of Internal Medicine, Rutgers Robert Wood Johnson Medical School, Saint Peter's University Hospital, New Brunswick, USA., Dastagir F; Department of Internal Medicine, St. George's University School of Medicine, Saint Peter's University Hospital, New Brunswick, USA., Khan AM; Department of Internal Medicine, St. George's University School of Medicine, Saint Peter's University Hospital, New Brunswick, USA., Redel H; Department of Infectious Diseases, Rutgers Robert Wood Johnson Medical School, Saint Peter's University Hospital, New Brunswick, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jul 10; Vol. 16 (7), pp. e64234. Date of Electronic Publication: 2024 Jul 10 (Print Publication: 2024).
DOI:	10.7759/cureus.64234
Abstrakt:	Shigellosis, a significant public health concern, has increasingly been recognized as a sexually transmitted infection (STI) among men who have sex with men (MSM), particularly in those with HIV. This case report describes a 25-year-old MSM with advanced HIV who presented with recurrent multidrug-resistant (MDR) Shigella flexneri infection despite multiple hospitalizations and antibiotic courses. The patient's high-risk sexual behaviors and suboptimal HIV management likely contributed to recurrent exposure to Shigella and the selection of resistant strains. This case highlights the complex interplay of individual behaviors, immune suppression, antimicrobial resistance, and the healthcare system in the context of this emerging STI. It underscores the importance of optimized HIV care, comprehensive patient education, robust healthcare coordination, and strengthened surveillance to effectively combat MDR shigellosis in vulnerable populations. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Bhatia et al.)
Databáze:	MEDLINE
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