Factors Affecting Survival in Severe and Very Severe COPD after Admission in ICUs of Tertiary Care Centers of India (FAST COPD): Study Protocol for a Multicentric Cohort Study.

Autor:	Arunachala S; Department of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru; Department of Critical Care Medicine, Adichunchanagiri Institute of Medical Sciences, Bellur; Department of Critical Care, ClearMedi Multispecialty Hospital, Mysuru, Karnataka, India., Devapal S; Mahadevappa Rampure Medical College, Kalaburagi, Karnataka, India., Swamy DSN; Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Greeshma MV; Center for Excellence in Molecular Biology and Regenerative Medicine (A DST-FIST Supported Center), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Ul Hussain I; Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Siddaiah JB; Department of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Christopher DJ; Department of Pulmonology, Christian Medical College, Vellore, Tamil Nadu, India., Malamardi S; Department of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India; School of Psychology & Public Health, College of Science Health and Engineering, La Trobe University, Melbourne, Australia., Ullah MK; Center for Excellence in Molecular Biology and Regenerative Medicine (A DST-FIST Supported Center), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India; Division of Infectious Disease and Vaccinology, School of Public Health, University of California, Berkeley, United States of America., Saeed M; Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Parthasarathi A; Rutgers University Institute for Health, Healthcare Policy, and Aging Research, The State University of New Jersey, New Brunswick, New Jersey, United States of America., Jeevan J; Department of Critical Care, ClearMedi Multispecialty Hospital, Mysuru, Karnataka, India., Kumar J; Department of Critical Care, ClearMedi Multispecialty Hospital, Mysuru, Karnataka, India., Harsha N; Department of Anaesthesiology, Adichunchanagiri Institute of Medical Sciences, Mysuru, Karnataka, India., Laxmegowda; Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Basavaraj CK; Department of Pediatrics, JSS Medical College, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India., Raghavendra PB; National Institute of Biomedical Genomics, Kalyani, West Bengal, India., Lokesh KS; Department of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Raj LN; Department of Critical Care, ClearMedi Multispecialty Hospital, Mysuru, Karnataka, India., Suneetha DK; Department of Medicine, Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Basavaraju MM; Department of Medicine, Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Kumar RM; Department of Medicine, Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Basavanagowdappa H; Department of Medicine, JSS Medical College, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India., Suma MN; Center for Excellence in Molecular Biology and Regenerative Medicine (A DST-FIST Supported Center), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Vishwanath PM; Center for Excellence in Molecular Biology and Regenerative Medicine (A DST-FIST Supported Center), Department of Biochemistry (A DST-FIST Supported Department), JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India., Babu S; Department of Medicine, JSS Medical College, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India., Ashok P; Department of Medicine, JSS Medical College, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India., Varsha T; Department of Medicine, JSS Medical College, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India., Chandran S; JSS Medical College, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India., Venkataraman H; JSS Medical College, JSS Academy of Higher Education & Research, Mysuru, Karnataka, India., Dinesh HN; Department of Surgery, Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Swaroop S; Mysore Medical College and Research Institute, Mysuru, Karnataka, India., Ganguly K; Unit of Integrative Toxicology, Institute of Environmental Medicine (IMM), Karolinska Institute, Stockholm, Sweden., Upadhyay S; Unit of Integrative Toxicology, Institute of Environmental Medicine (IMM), Karolinska Institute, Stockholm, Sweden., Mahesh PA; Department of Respiratory Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.
Jazyk:	angličtina
Zdroj:	Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine [Indian J Crit Care Med] 2024 Jun; Vol. 28 (6), pp. 552-560.
DOI:	10.5005/jp-journals-10071-24728
Abstrakt:	Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. However, there is a lack of comprehensive data from low- and middle-income countries (LMICs) regarding factors influencing COPD outcomes, particularly in regions where biomass exposure is prevalent. Objective: The Factors Affecting Survival in Severe and Very Severe COPD Patients Admitted to Tertiary Centers of India (FAST) study aims to address this gap by evaluating factors impacting survival and exacerbation rates among COPD patients in LMICs like India, with a specific focus on biomass exposure, clinical phenotypes, and nutritional status in patients admitted to the Intensive Care Unit (ICU). Methods: The FAST study is an observational cohort study conducted in university teaching hospitals across India. The study aims to enroll 1000 COPD patients admitted to the ICU meeting specific inclusion criteria, with follow-up assessments conducted every 6 months over a 2-year period. Data collection includes demographic information, clinical manifestations, laboratory investigations, pulmonary function tests, medications, nutritional status, mental health, and health-related quality of life. Adjudication of exacerbations and mortality will also be undertaken. The FAST study seeks to provide crucial insights into COPD outcomes in LMICs, informing more precise management strategies and mitigating the burden of COPD in these settings. By evaluating factors such as biomass exposure, clinical phenotypes, and nutritional status, the study aims to address key knowledge gaps in COPD research. How to Cite This Article: Arunachala S, Devapal S, Swamy DSN, Greeshma MV, Ul Hussain I, Siddaiah JB, et al . Factors Affecting Survival in Severe and Very Severe COPD after Admission in ICUs of Tertiary Care Centers of India (FAST COPD): Study Protocol for a Multicentric Cohort Study. Indian J Crit Care Med 2024;28(6):552-560. Competing Interests: Source of support: Nil Conflict of interest: None (Copyright © 2024; The Author(s).)
Databáze:	MEDLINE
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