The effects of cannabis use on major adverse cardiovascular outcomes, mortality, cost of hospitalization, and cardiac arrhythmias: A Retrospective analysis using the national inpatient sample.

Autor: Elsadek R; University of Central Florida College of Medicine, Graduate Medical Education / HCA Florida North Florida Hospital, Internal Medicine Residency Program, 1147 NW 64th Terrace, 6500 W Newberry Rd, Gainesville, FL 32605, United States. Electronic address: rabab.elsadek2@gmail.com., Ismail Z; HCA Florida Aventura Hospital, Cardiovascular Disease Fellowship Program, 20900 Biscayne Blvd, Aventura, FL 33180, United States., Al-Ani H; University of Central Florida College of Medicine, Graduate Medical Education / HCA Florida North Florida Hospital, Internal Medicine Residency Program, 1147 NW 64th Terrace, 6500 W Newberry Rd, Gainesville, FL 32605, United States., Loseke I; University of Central Florida College of Medicine, Graduate Medical Education / HCA Florida North Florida Hospital, Internal Medicine Residency Program, 1147 NW 64th Terrace, 6500 W Newberry Rd, Gainesville, FL 32605, United States., Fikry M; National Heart Institute, 5 Ibn-Al-Nafees Square, Giza, Egypt., Meadows R; Research Analyst, Graduate Medical Education, Physician Services Group, HCA Healthcare, 2000 Health Park Drive, Brentwood, TN 37027, United States., Zentko S; Division of Cardiology, Department of Internal Medicine, HCA Florida North Florida Hospital, 6500 W Newberry Road. Gainesville, FL 32605, United States., Curry B; Division of Cardiology, Department of Internal Medicine, HCA Florida Aventura Hospital, 20900 Biscayne Blvd, Aventura, FL 33180, United States.
Jazyk: angličtina
Zdroj: Current problems in cardiology [Curr Probl Cardiol] 2024 Nov; Vol. 49 (11), pp. 102788. Date of Electronic Publication: 2024 Aug 08.
DOI: 10.1016/j.cpcardiol.2024.102788
Abstrakt: As cannabis use is rising and federal restrictions are easing, it is important to recognize its potential adverse cardiovascular effects for better risk stratification and informed guidance. We conducted a retrospective study using the National Inpatient Sample database from 2016 to 2019, where 39,992 subjects were enrolled. The extracted population was classified into two groups based on the presence of cannabis-related disorders. The primary outcomes of the study were cardiovascular-related adverse events, in-hospital mortality, total cost of hospitalization, and cardiac dysrhythmias. The study concluded that cannabis use disorder was not significantly associated with the likelihood of having a cardiovascular adverse event, cardiac dysrhythmias, or with the cost of hospitalization when controlling for other variables (p = 0.257, p=0.481 & p = 0.481, respectively). However, it was significantly associated with the likelihood of mortality (p < 0.0001). Further randomized trials are needed to confirm these findings and elaborate on identified associations.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Published by Elsevier Inc.)
Databáze: MEDLINE
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