Field-Directed Motion, Cargo Capture, and Closed-Loop Controlled Navigation of Microellipsoids.

Autor: Gauri HM; Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA, 70803, USA., Patel R; Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA, 70803, USA., Lombardo NS; Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA, 70803, USA., Bevan MA; Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA., Bharti B; Cain Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA, 70803, USA.
Jazyk: angličtina
Zdroj: Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Oct; Vol. 20 (43), pp. e2403007. Date of Electronic Publication: 2024 Aug 10.
DOI: 10.1002/smll.202403007
Abstrakt: Microrobots have the potential for diverse applications, including targeted drug delivery and minimally invasive surgery. Despite advancements in microrobot design and actuation strategies, achieving precise control over their motion remains challenging due to the dominance of viscous drag, system disturbances, physicochemical heterogeneities, and stochastic Brownian forces. Here, a precise control over the interfacial motion of model microellipsoids is demonstrated using time-varying rotating magnetic fields. The impacts of microellipsoid aspect ratio, field characteristics, and magnetic properties of the medium and the particle on the motion are investigated. The role of mobile micro-vortices generated is highlighted by rotating microellipsoids in capturing, transporting, and releasing cargo objects. Furthermore, an approach is presented for controlled navigation through mazes based on real-time particle and obstacle sensing, path planning, and magnetic field actuation without human intervention. The study introduces a mechanism of directing motion of microparticles using rotating magnetic fields, and a control scheme for precise navigation and delivery of micron-sized cargo using simple microellipsoids as microbots.
(© 2024 Wiley‐VCH GmbH.)
Databáze: MEDLINE
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