Engineering Lipid-Based Pop-up Conductive Interfaces with PEDOT:PSS and Light-Responsive Azopolymer Films.

Autor: Terenzi L; Institute of Biological Information Processing - Bioelectronics, IBI-3, Forschungszentrum Jülich, 52428, Jülich, Germany.; Neuroelectronic Interfaces, RWTH Aachen, 52074, Aachen, Germany., Gao Z; Institute of Biological Information Processing - Bioelectronics, IBI-3, Forschungszentrum Jülich, 52428, Jülich, Germany.; Neuroelectronic Interfaces, RWTH Aachen, 52074, Aachen, Germany., Ravandeh M; Institute of Biological Information Processing - Bioelectronics, IBI-3, Forschungszentrum Jülich, 52428, Jülich, Germany.; Neuroelectronic Interfaces, RWTH Aachen, 52074, Aachen, Germany., Fedele C; Faculty of Engineering and Natural Sciences, Tampere University, Tampere, FI-33720, Finland., Klausen LH; Interdisciplinary Nanoscience Center - INANO-Fysik, Aarhus University, Aarhus, 8000, Denmark., Bovio CL; Center for Advanced Biomaterials for Healthcare, Italian Institute of Technology, Naples, 80125, Italy.; Dipartimento di Chimica, Materiali e Produzione Industriale, University Federico II of Naples, Naples, 80125, Italy., Priimagi A; Faculty of Engineering and Natural Sciences, Tampere University, Tampere, FI-33720, Finland., Santoro F; Institute of Biological Information Processing - Bioelectronics, IBI-3, Forschungszentrum Jülich, 52428, Jülich, Germany.; Neuroelectronic Interfaces, RWTH Aachen, 52074, Aachen, Germany.; Center for Advanced Biomaterials for Healthcare, Italian Institute of Technology, Naples, 80125, Italy.
Jazyk: angličtina
Zdroj: Advanced healthcare materials [Adv Healthc Mater] 2024 Sep; Vol. 13 (24), pp. e2303812. Date of Electronic Publication: 2024 Aug 09.
DOI: 10.1002/adhm.202303812
Abstrakt: Significant challenges have emerged in the development of biomimetic electronic interfaces capable of dynamic interaction with living organisms and biological systems, including neurons, muscles, and sensory organs. Yet, there remains a need for interfaces that can function on demand, facilitating communication and biorecognition with living cells in bioelectronic systems. In this study, the design and engineering of a responsive and conductive material with cell-instructive properties, allowing for the modification of its topography through light irradiation, resulting in the formation of "pop-up structures", is presented. A deformable substrate, composed of a bilayer comprising a light-responsive, azobenzene-containing polymer, pDR1m, and a conductive polymer, PEDOT:PSS, is fabricated and characterized. Moreover, the successful formation of supported lipid bilayers (SLBs) and the maintenance of integrity while deforming the pDR1m/PEDOT:PSS films represent promising advancements for future applications in responsive bioelectronics and neuroelectronic interfaces.
(© 2024 The Author(s). Advanced Healthcare Materials published by Wiley‐VCH GmbH.)
Databáze: MEDLINE
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