Perspectives and Possibilities for New Antimicrobial Agents in the Treatment and Control of Mastitis Induced by Algae of the Genus Prototheca spp.: A Review.

Autor: Jabłońska W; Department of Animal Breeding, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-787 Warsaw, Poland., Gołębiewski M; Department of Animal Breeding, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-787 Warsaw, Poland., Kot M; Department of Animal Breeding, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-787 Warsaw, Poland., Mardan H; Department of Animal Breeding, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-787 Warsaw, Poland., Pawliński B; Department of Large Animal Diseases and Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-787 Warsaw, Poland., Kalińska A; Department of Animal Breeding, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Jazyk: angličtina
Zdroj: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 27; Vol. 25 (15). Date of Electronic Publication: 2024 Jul 27.
DOI: 10.3390/ijms25158219
Abstrakt: Innovative approaches in nanotechnology provide a potentially promising alternative to untreatable cases of mastitis caused by genus Prototheca spp. algae infections. Drying of the teats of the affected animals or culling are typically the outcomes of mastitis in dairy cattle caused by these pathogens. A major issue in both veterinary medicine and animal breeding is the Prototheca species' widespread resistance to the current methods of managing infections and the available drugs, including antibiotics. Commercial antifungal preparations are also ineffective. Nanotechnology, an emerging discipline, has the potential to create an effective alternative treatment for protothecal mastitis . The aim of the paper is to combine the literature data on the use of nanotechnology in the control of mastitis , taking into account data on combating mastitis caused by Prototheca spp. infections. The databases employed were PubMed, Google Scholar, and Scopus, focusing on literature from the last 20 years to ensure relevance and currency. Studies conducted in vitro have demonstrated that nanomaterials have significant biocidal activity against mastitis infections of different etiologies. Analyzed research papers show that (NPs), such as AgNPs, CuNPs, AuNPs, etc., may not negatively impact various cell lines and may be effective agents in reducing the pathogens' viability. However, it is also critical to assess the risks involved in using nanomaterials.
Databáze: MEDLINE
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