Outcomes of Bariatric Surgery in Patients with Schizophrenia.

Autor:	Miñambres I; Servicio de Endocrinología, Hospital de La Santa Creu i Sant Pau, 08041 Barcelona, Spain.; CIBER de Diabetes y Enfermedades Metabólicas (CIBERDEM), 28029 Madrid, Spain.; Departament de Medicina, Universitat Autònoma de Barcelona (UAB), 08193 Bellaterra, Spain., Rubio-Herrera MÁ; Servicio de Endocrinología y Nutrición, Hospital Clínico San Carlos, 28040 Madrid, Spain.; Departamento de Medicina, Universidad Complutense, 28040 Madrid, Spain., Nicolau J; Servicio de Endocrinología, Hospital de Son Llàtzer, 07198 Mallorca, Spain., Milad C; Servicio de Endocrinología, Hospital Clínic de Barcelona, 08036 Barcelona, Spain., Morales MJ; Servicio de Endocrinología, Complexo Hospitalario Universitario de Vigo, 36312 Pontevedra, Spain., Bueno M; Servicio de Endocrinología y Nutrición, Hospital Universitari Arnau de Vilanova, 25198 Lleida, Spain.; Obesity, Diabetes and Metabolism (ODIM) Research Group, Institut de Recerca Biomèdica Lleida (IRB-Lleida), 25198 Lleida, Spain., Calañas A; Servicio de Endocrinología, Hospital Universitario Reina Sofía, 14004 Córdoba, Spain., Carceller-Sindreu M; Servicio de Psiquiatría, Hospital de La Santa Creu i Sant Pau, 08041 Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), 28029 Madrid, Spain.; Institut d'Investigació Biomèdica Sant Pau (IIB-Sant Pau), 08041 Barcelona, Spain., de Hollanda A; Servicio de Endocrinología, Hospital Clínic de Barcelona, 08036 Barcelona, Spain.; Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBEROBN), 28029 Madrid, Spain.
Jazyk:	angličtina
Zdroj:	Nutrients [Nutrients] 2024 Jul 31; Vol. 16 (15). Date of Electronic Publication: 2024 Jul 31.
DOI:	10.3390/nu16152487
Abstrakt:	Background: Outcomes of bariatric surgery (BS) in patients with schizophrenia are poorly understood. We aimed to analyze the effects of BS in patients with schizophrenia (SZ) or schizoaffective disorder (SZA). Methods: This was a multicenter, retrospective case-control study in patients with SZ or SZA who had undergone BS in seven public referral hospitals in Spain. Controls without psychiatric comorbidity were selected in a 1:4 ratio. Detailed clinical and biochemical data were collected preoperatively and at 12, 24, 36, 48, and 60 months after BS. Results: Twenty patients with SZ ( n = 15; 75%) or SZA ( n = 5; 25%) and 80 matched controls were studied. There were no differences between patients and controls concerning the evolution of the percentage of total weight loss. The remission rate of the main comorbidities was similar between groups except for hypertension, which was lower in patients with a psychotic disorder from year 3. There were no mortalities within 30 days of surgery in either group. The psychiatric medication burden did not change during follow-up. Conclusions: BS is safe and effective in carefully selected patients with SZ. The course of the psychiatric disease does not seem to be worsened by the procedure.
Databáze:	MEDLINE
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