Prospective evaluation of ultrasonographic fetal cardiac morphometry and functions in the third trimester of pregnancies with gestational diabetes mellitus.

Autor: Duygulu D; Department of Obstetrics and Gynaecology, Gazi University, Ankara, Turkey., Mutlu Sütcüoğlu B; Department of Obstetrics and Gynaecology, Ankara Atatürk Sanatoryum Research and Training Hospital, Ankara, Turkey., Turgut E; Department of Perinatology, Gazi University, Ankara, Turkey., Özdemir H; Department of Perinatology, Gazi University, Ankara, Turkey., Karçaaltıncaba D; Department of Perinatology, Gazi University, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Journal of clinical ultrasound : JCU [J Clin Ultrasound] 2024 Nov-Dec; Vol. 52 (9), pp. 1265-1272. Date of Electronic Publication: 2024 Aug 09.
DOI: 10.1002/jcu.23776
Abstrakt: Objective: This study aimed to compare cardiac morphological and functional changes in fetuses of patients with diet-regulated gestational diabetes mellitus (GDM-A1), insulin-regulated GDM (GDM-A2), and a control group.
Method: A prospective cohort study included pregnant women aged 18-40 years with singleton pregnancies. Fetal biometric, cardiac morphological, and functional measurements were recorded using Z-scores at 34-37 weeks of gestation.
Results: The study included 87 patients. Both right and left ventricular wall thicknesses were significantly different between the three groups (p < 0.001 and p < 0.001, respectively). Z-scores of the mitral valve, left and right EDD were significantly lower in GDM-A1 and GDM-A2 groups compared to the control group (p < 0.001, p < 0.001, p = 0.002, respectively). Right and left ventricular areas were decreased only in GDM-A2 group compared to the control group (p = 0.003 and p = 0.001, respectively). MPI and IVRT values were also significantly higher in the same groups (p = 0.016, p < 0.001, respectively).
Conclusion: Gestational diabetes increased IVS and ventricular wall thicknesses in both right and left ventricles, irrespective of whether it was controlled by diet or insulin. Cardiac functional changes were observed in the GDM-A2 group.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
Externí odkaz: