Direct toll-like receptor triggering in colorectal cancer-associated stromal cells elicits immunostimulatory properties leading to enhanced immune cell recruitment.

Autor: Djordjevic J; Laboratory for Surgical Research, EOC Laboratories for Translational Research, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland., Cisneros Romero NS; Faculty of Natural Sciences, University of Basel, Basel, Switzerland.; Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Cascione L; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Bioinformatics Core Unit, Institute of Oncology Research (IOR), Bellinzona, Switzerland., Mele V; Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Cremonesi E; Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland., Sorrenti E; Laboratory for Surgical Research, EOC Laboratories for Translational Research, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland., Basso C; Laboratory for Surgical Research, EOC Laboratories for Translational Research, Bellinzona, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland., Villa M; Laboratory for Surgical Research, EOC Laboratories for Translational Research, Bellinzona, Switzerland., Cianfarani A; Laboratory for Surgical Research, EOC Laboratories for Translational Research, Bellinzona, Switzerland.; Department of Surgery, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland., Roesel R; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Department of Surgery, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland., Galafassi J; Department of Surgery, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland., Majno-Hurst PE; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Department of Surgery, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland., Spagnoli G; Institute of Translational Pharmacology, National Research Council, Roma, Italy., Christoforidis D; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.; Department of Surgery, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland., Iezzi G; Laboratory for Surgical Research, EOC Laboratories for Translational Research, Bellinzona, Switzerland giandomenica.iezzi@eoc.ch.; Faculty of Biomedical Sciences, Università della Svizzera italiana, Lugano, Switzerland.
Jazyk: angličtina
Zdroj: Gut [Gut] 2024 Aug 08. Date of Electronic Publication: 2024 Aug 08.
DOI: 10.1136/gutjnl-2023-331759
Abstrakt: Competing Interests: Competing interests: None declared.
Databáze: MEDLINE