Actin network evolution as a key driver of eukaryotic diversification.
| Autor: | Velle KB; Department of Biology, University of Massachusetts Dartmouth, Dartmouth, MA 02747, USA., Swafford AJM; Department of Biology, Middlebury College, Middlebury, VT 05753, USA., Garner E; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA., Fritz-Laylin LK; Department of Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of cell science [J Cell Sci] 2024 Aug 01; Vol. 137 (15). Date of Electronic Publication: 2024 Aug 09. |
| DOI: | 10.1242/jcs.261660 |
| Abstrakt: | Eukaryotic cells have been evolving for billions of years, giving rise to wildly diverse cell forms and functions. Despite their variability, all eukaryotic cells share key hallmarks, including membrane-bound organelles, heavily regulated cytoskeletal networks and complex signaling cascades. Because the actin cytoskeleton interfaces with each of these features, understanding how it evolved and diversified across eukaryotic phyla is essential to understanding the evolution and diversification of eukaryotic cells themselves. Here, we discuss what we know about the origin and diversity of actin networks in terms of their compositions, structures and regulation, and how actin evolution contributes to the diversity of eukaryotic form and function. Competing Interests: Competing interests The authors declare no competing or financial interests. (© 2024. Published by The Company of Biologists Ltd.) |
| Databáze: | MEDLINE |
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