Calcium polystyrene sulfonate-induced colitis: advanced characterization of crystal nature with infrared spectroscopy.

Autor: Vidal H; Nephrology Department, Local Health Unit of Saint Joseph - Curry Cabral Hospital, Lisbon, Portugal.; Nephrology Department, Hospital do Divino Espírito Santo de Ponta Delgada, Azores-São Miguel, Portugal.; Lisbon Clinical Academic Center, Lisbon, Portugal., Salgado V; Lisbon Clinical Academic Center, Lisbon, Portugal.; Pathology Department, Centro Hospitalar Universitário de Lisboa Central EPE, Lisbon, Portugal., Alves P; Nephrology Department, Local Health Unit of Saint Joseph - Curry Cabral Hospital, Lisbon, Portugal.; Lisbon Clinical Academic Center, Lisbon, Portugal., Fonseca NM; Nephrology Department, Local Health Unit of Saint Joseph - Curry Cabral Hospital, Lisbon, Portugal.; Lisbon Clinical Academic Center, Lisbon, Portugal.; Nova Medical School, Nova University of Lisbon, Lisbon, Portugal., Frochot V; Physiology Department, Hôpital Tenon, APHP, Paris, France.; Faculty of Medicine, Pierre et Marie Curie University, Paris, France.; INSERM UMRS 1155, Paris, France., Ferreira A; Nephrology Department, Local Health Unit of Saint Joseph - Curry Cabral Hospital, Lisbon, Portugal.; Lisbon Clinical Academic Center, Lisbon, Portugal.; Nova Medical School, Nova University of Lisbon, Lisbon, Portugal.
Jazyk: angličtina
Zdroj: Clinical kidney journal [Clin Kidney J] 2024 Jul 08; Vol. 17 (8), pp. sfae210. Date of Electronic Publication: 2024 Jul 08 (Print Publication: 2024).
DOI: 10.1093/ckj/sfae210
Abstrakt: Classical potassium binders are used in the treatment of hyperkalemia and are widely associated with gastrointestinal side effects, with crystal colonic injury being rare but potentially fatal. In this report, we describe the case of an 82-year-old male with hyperkalemia and calcium polystyrene sulfonate crystal-associated colonic necrosis. Traditionally, this diagnosis has relied on the examination of crystal morphology and polarization through microscopy. Our study enhances crystal identification by incorporating an analysis of the physical characteristics of the crystals using infrared spectroscopy. This is the first description, to our knowledge, of the calcium polystyrene sulfonate infrared spectrum.
Competing Interests: No conflict of interest needs to be declared by the authors.
(© The Author(s) 2024. Published by Oxford University Press on behalf of the ERA.)
Databáze: MEDLINE
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