Role of Computed Tomography in Prediction of Depth of Invasion and Cervical Lymph Node Metastasis in Oral Cancer.

Autor: Kottakota V; Department of Surgical Oncology, HCG Cancer Centre, APIIC Health City, Arilova, Visakhapatnam, Andhra Pradesh 530040 India., Sarkar DF; Department of Surgical Oncology, HCG Cancer Centre, APIIC Health City, Arilova, Visakhapatnam, Andhra Pradesh 530040 India., Tadepalli VNS; Department of Surgical Oncology, HCG Cancer Centre, APIIC Health City, Arilova, Visakhapatnam, Andhra Pradesh 530040 India., Yadaraju VA; Department of Radiation Oncology, HCG Cancer Centre, APIIC Health City, Arilova, Visakhapatnam, Andhra Pradesh 530040 India., Muralidhar KB; Department of Surgical Oncology, HCG Cancer Centre, APIIC Health City, Arilova, Visakhapatnam, Andhra Pradesh 530040 India., Kotne S; Department of Medical Oncology, HCG Cancer Centre, APIIC Health City, Arilova, Visakhapatnam, Andhra Pradesh 530040 India., Bora M; Department of Radiation Oncology, HCG Cancer Centre, APIIC Health City, Arilova, Visakhapatnam, Andhra Pradesh 530040 India., Lagudu PBB; Department of Medical Oncology, HCG Cancer Centre, APIIC Health City, Arilova, Visakhapatnam, Andhra Pradesh 530040 India.
Jazyk: angličtina
Zdroj: Journal of maxillofacial and oral surgery [J Maxillofac Oral Surg] 2024 Aug; Vol. 23 (4), pp. 856-863. Date of Electronic Publication: 2024 Jun 19.
DOI: 10.1007/s12663-024-02265-7
Abstrakt: Objectives: The primary aim is to determine the accuracy of contrast-enhanced computed tomography (CT) in evaluation of depth of invasion (DOI) and detection of cervical node metastasis. We also analysed the relation between radiographic DOI (rDOI) and cervical lymph node metastasis.
Materials and Methods: We have retrospectively reviewed 201 oral squamous cell carcinoma (SCC) patients. The rDOI was compared with histological DOI. Sensitivity, specificity, accuracy, and negative (NPV) and positive (PPV) predictive values were evaluated for CT scan in predicting nodal metastasis. The relation between rDOI and lymph node metastasis was analysed using ROC curve.
Results: rDOI correlated significantly with histologic DOI for oral tongue, buccal mucosa, gingiva, and mucosal lip SCC ( P  < 0.05) and for tumours with rDOI > 5 mm. The sensitivity, specificity, PPV, NPV and accuracy rate of CT scan were found to be 84.71%, 50.86%, 55.81%, 81.94% and 65.17%, respectively. Tumours with rDOI > 16 mm had significant ( P  < 0.001) chance of having neck node metastasis.
Conclusion: CT-derived DOI correlates significantly with pathological DOI although both are not similar. CT scan can predict nodal metastasis in fairly accurate manner using the four radiographic criteria used in this study. Radiographic depth of invasion can be used as predictor of cervical node metastasis.
Competing Interests: Conflict of interestThe authors have no competing interests to declare that are relevant to the content of this article.
(© The Association of Oral and Maxillofacial Surgeons of India 2024. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
Databáze: MEDLINE
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