Demystifying Functional Parameters for Irreversible Enzyme Inhibitors.

Autor: Heppner DE; Department of Chemistry, The State University of New York at Buffalo. Buffalo, New York 14221, United States., Ogboo BC; Department of Chemistry, The State University of New York at Buffalo. Buffalo, New York 14221, United States., Urul DA; AssayQuant Technologies Inc., Marlboro, Massachusetts 01752, United States., May EW; AssayQuant Technologies Inc., Marlboro, Massachusetts 01752, United States., Schaefer EM; AssayQuant Technologies Inc., Marlboro, Massachusetts 01752, United States., Murkin AS; Department of Chemistry, The State University of New York at Buffalo. Buffalo, New York 14221, United States., Gehringer M; Division of Medicinal Chemistry, Institute of Biomedical Engineering, University Hospital Tübingen and Institute of Pharmaceutical Sciences, University of Tübingen. 72076 Tübingen, Germany.
Jazyk: angličtina
Zdroj: Journal of medicinal chemistry [J Med Chem] 2024 Sep 12; Vol. 67 (17), pp. 14693-14696. Date of Electronic Publication: 2024 Aug 08.
DOI: 10.1021/acs.jmedchem.4c01721
Databáze: MEDLINE