| Autor: |
Grove K, Cavalheri V, Chih H, Natarajan V, Harrold M, Mohd S, Hurn E, Van der Lee L, Maiorana A, Tearne J, Watson C, Pearce J, Jacques A, White A, Vicary C, Roffman C, Synnott EL, Suttie I, Lin I, Larsson J, Naylor L, Woodhouse L, Elliott M, Gittings P, Winship P, Timms R, Wulff S, Hebden-Todd T, Edgar DW |
| Jazyk: |
angličtina |
| Zdroj: |
Australian health review : a publication of the Australian Hospital Association [Aust Health Rev] 2024 Aug 08. Date of Electronic Publication: 2024 Aug 08. |
| DOI: |
10.1071/AH23271 |
| Abstrakt: |
ObjectiveThis study aimed to compare the relative physical recovery and symptoms after SARS-CoV-2 infection between groups confirmed positive or negative to early strains of COVID-19.MethodsA prospective, longitudinal cohort study compared outcomes of metropolitan adults polymerase chain reaction-tested for COVID-19 between March and November 2020 in Western Australia. Control matching was attempted: inpatients (gender, age) and ambulatory clinic (gender, age, asthma, chronic pulmonary disease). One-year follow-up involved three repeated measures: physical function (grip strength and 1-min sit-to-stand) and patient-reported outcomes (Fatigue Severity Scale, modified Medical Research Council dyspnoea scale and Euroqol-5D-5L).ResultsThree hundred and forty-four participants were recruited (154 COVID+, age 54±18years, 75 females [49%]); 190 COVID-, age 52±16years, 67 females [35%]) prior to national vaccination roll-out. No between-group differences in physical function measures were evident at any time point. Fatigue (OR 6.62, 95% CI 2.74-15.97) and dyspnoea (OR 2.21, 95% CI 1.14-4.30) were higher in the COVID+ group at second assessment (T2). On Euroqol-5D-5L, no between-group differences were evident in the physical function domains of self-care, mobility or usual activities at any time point. However, COVID+ participants were less likely to report an absence of anxiety or depression symptoms at T2 (OR 0.41, 95% CI 0.19-0.89).ConclusionsNeither statistical nor clinically meaningful differences in physical function were evident between COVID+ and COVID- participants to 12-months after acute illness. Symptoms of fatigue, dyspnoea, anxiety or depression were more prevalent in the COVID+ group til ~8months after illness with between-group differences no longer evident at 1 year. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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