Tendon involvement and its association with pain and hand function in patients with osteoarthritis of the hand.

Autor:	Gessl I; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Vinatzer A; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Supp G; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Zauner M; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Durechova M; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Lechner L; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Ritschl V; Institute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria., Smolen J; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Stamm T; Institute of Outcomes Research, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria., Aletaha D; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria., Mandl P; Division of Rheumatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria.; Ludwig Boltzmann Institute for Arthritis and Rehabilitation, Vienna, Austria.
Jazyk:	angličtina
Zdroj:	Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2024 Aug 07. Date of Electronic Publication: 2024 Aug 07.
DOI:	10.1093/rheumatology/keae395
Abstrakt:	Objective: To characterise the frequency and influence of tenosynovitis and tendon damage on pain and hand function using clinical examination and ultrasound (US) in hand osteoarthritis (HOA). Methods: We included 86 patients with HOA and 23 age- and sex-matched control subjects. Extensor and flexor tendons of both hands were assessed by clinical examination and US for tenosynovitis, tendon damage. Conventional radiographs were acquired. Hand function was evaluated by the function subtest of the M-SACRAH questionnaire and the Moberg pick-up test. K-means cluster analyses was calculated to assess clusters based on radiographic features and sonographic tendon scores. Results: Ultrasound identified the involvement of ≥ 1 tendon in 60/86 (69.8%) HOA patients compared with 2/23 (8.7%) subjects (p< 0.01) in the control group. In the HOA group, US detected tendon damage more often in flexor tendons compared with extensor tendons (2.1% 0.9%, p= 0.03), while tenosynovitis was observed more often in extensor tendons compared with flexor tendons (8% vs 0.6%, p< 0001). The sensitivity and specificity of clinical examination to detect tendon involvement was 81.4% and 34.6%, respectively on the patient level and 14.5% and 83.8% on the tendon level. The cluster analyses revealed one cluster with more radiographic features of HOA and more tendon damage while more tenosynovitis was found in cluster 2. M-SACRAH function did not correlate with tendon involvement on US. Conclusion: This study revealed a high frequency of tendon involvement in HOA. Tendon involvement on US did not impact hand function or self-reported pain. (© The Author(s) 2024. Published by Oxford University Press on behalf of the British Society for Rheumatology.)
Databáze:	MEDLINE
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