Predictors of the onset of low handgrip strength in Europe: a longitudinal study of 42,183 older adults from 15 countries.

Autor: Qaisar R; Basic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Space Medicine Research Group, Research Institute for Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Cardiovascular Research Group, Research Institute for Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates., Hussain MA; Department of Finance and Economics, College of Business Administration, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Department of Social Sciences and Business, Roskilde University, DK-4000, Roskilde, Denmark., Franzese F; SHARE Berlin Institute, Chausseestraße 111, 10115, Berlin, Germany., Karim A; Basic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates., Ahmad F; Basic Medical Sciences, College of Medicine, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Space Medicine Research Group, Research Institute for Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates.; Cardiovascular Research Group, Research Institute for Medical and Health Sciences, University of Sharjah, 27272, Sharjah, United Arab Emirates., Awad A; Department of Finance and Economics, College of Business Administration, University of Sharjah, 27272, Sharjah, United Arab Emirates., Al-Masri AA; Department of Physiology, College of Medicine, King Saud University, 11451, Riyadh, Saudi Arabia., Alkahtani SA; Exercise Physiology Department, College of Sport Sciences and Physical Activity, King Saud University, 11451, Riyadh, Saudi Arabia. shalkahtani@ksu.edu.sa.
Jazyk: angličtina
Zdroj: Aging clinical and experimental research [Aging Clin Exp Res] 2024 Aug 07; Vol. 36 (1), pp. 162. Date of Electronic Publication: 2024 Aug 07.
DOI: 10.1007/s40520-024-02800-z
Abstrakt: Objectives: A low handgrip strength (HGS) is a significant risk factor for multiple diseases. However, most relevant studies investigate the complications of a low HGS, while the risk potential of causative factors of low HGS remain poorly characterized.
Methods: We investigated the potentials of quality of life, depression, dyslipidaemia, diabetes mellitus, cancer, Alzheimer's disease, stroke, frailty, and difficulties performing daily activities in predicting low HGS (≤ 27 kg for men, ≤ 16 kg for women) in European older adults aged 50 or above from 15 countries (n = 42,183). All data was collected from four successive waves of survey of health, ageing, and retirement in Europe (SHARE) conducted between 2013 and 2020. Logistic models are applied, and estimated effects are presented as odds ratios and probabilities.
Results: Collectively, 3016 participants (men; n = 1395; 7.38%, women; n = 1621, 6.97%) developed low HGS during the 6.5 years study period. After adjusting for covariables, we identified an advancing age (1.6-48.1% points higher risk of low HGS), male gender (1.0%-point higher risk of low HGS), lower quality of life (1.6%-point higher), and stroke (1.5%-points) as significant risk factors for low HGS. We also found a dose-dependent association of Euro-D depression scores with the risk of low HGS, as the higher scores were associated with between 0.6- and 2.3%-points higher risk of developing low HGS than participants without depression. Among physical performance indicators, difficulty climbing stairs (2.0%-points higher low HGS risk) or rising from a chair (0.7%-points) were significantly associated with developing low HGS. Lastly, frailty (0.9%-points higher risk of low HGS) and the fear of falling down (1.6%-points higher risk) also increased the risk of developing low HGS.
Conclusion: Altogether, we report several risk factors for developing low HGS. Our observations may help evaluating and monitoring high-risk population for developing low HGS in pre-clinical settings.
(© 2024. The Author(s).)
Databáze: MEDLINE
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