Detection of lumpy skin disease virus reads in the human upper respiratory tract microbiome requires further investigation.

Autor: Tomar SS; Environmental Epidemiology and Pandemic Management (EE&PM), Council of Scientific and Industrial Research-National Environmental Engineering Research Institute (CSIR-NEERI), Nagpur, Maharashtra, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India., Khairnar K; Environmental Epidemiology and Pandemic Management (EE&PM), Council of Scientific and Industrial Research-National Environmental Engineering Research Institute (CSIR-NEERI), Nagpur, Maharashtra, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh, India.
Jazyk: angličtina
Zdroj: Journal of medical virology [J Med Virol] 2024 Aug; Vol. 96 (8), pp. e29829.
DOI: 10.1002/jmv.29829
Abstrakt: Lumpy skin disease virus (LSDV), a double-stranded DNA virus from the Capripoxvirus genus, primarily affects Bos indicus, Bos taurus breeds, and water buffalo. Arthropod vectors, including mosquitoes and biting flies, are the main LSDV transmitters. Although LSDV is not zoonotic, this study unexpectedly detected LSDV reads in the upper respiratory tract microbiome of humans from rural and urban areas in Maharashtra, India. Nasopharyngeal and oropharyngeal swab samples collected for SARS-CoV-2 surveillance underwent whole-genome metagenomics sequencing, revealing LSDV reads in 25% of samples. Split kmer analysis provided insights into sample relatedness despite the low coverage of LSDV reads with the reference genome. Our findings, which include the detection of LSDV contigs aligning to specific locations on the reference genome, suggest a common source for LSDV reads, potentially shared water sources, or milk/milk products. Further investigation is needed to ascertain the mode of transmission and reason for the detection of LSDV reads in human upper respiratory tract.
(© 2024 Wiley Periodicals LLC.)
Databáze: MEDLINE
Externí odkaz: