Primordial Odontogenic Tumor: A Review of the Literature and Report of Three New Patients.

Autor:	Cavalcante IL; Department of Dentistry, University of Fortaleza (UNIFOR), Fortaleza, CE, Brazil.; Department of Oral Diagnosis and Pathology, Postgraduate Program in Dentistry, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil., Barros CCDS; Department of Dentistry, Postgraduate Program in Dental Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil., Sousa Cruz VM; Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, SP, Brazil., Costa MB; Traumatology and Bucomaxillofacial Surgery, General Hospital of Fortaleza, Fortaleza, CE, Brazil., da Silveira Santos DF; Traumatology and Bucomaxillofacial Surgery, General Hospital of Fortaleza, Fortaleza, CE, Brazil., de León-Garza B; Hospital Issste Puebla, Puebla, Mexico., Parra-Salazar MA; Hospital Issste Puebla, Puebla, Mexico., Cruz-Tapia RO; National Autonomous University of Mexico, Mexico City, Mexico., Rodriguez B; Maxillofacial Surgery Service, General Hospital of the West, Dr José Gregorio Hernández, Caracas, Venezuela., Manresa C; Maxillofacial Surgery Service, General Hospital of the West, Dr José Gregorio Hernández, Caracas, Venezuela., Sánchez G; Maxillofacial Surgery Service, General Hospital of the West, Dr José Gregorio Hernández, Caracas, Venezuela., Villarroel-Dorrego M; Master's Program in Stomatologic Medicine, Universidad Central de Venezuela, Caracas, Venezuela., Turatti E; Department of Dentistry, University of Fortaleza (UNIFOR), Fortaleza, CE, Brazil., Cavalcante RB; Department of Dentistry, University of Fortaleza (UNIFOR), Fortaleza, CE, Brazil., de Andrade BAB; Department of Oral Diagnosis and Pathology, Postgraduate Program in Dentistry, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.
Jazyk:	angličtina
Zdroj:	International journal of surgical pathology [Int J Surg Pathol] 2024 Aug 06, pp. 10668969241266925. Date of Electronic Publication: 2024 Aug 06.
DOI:	10.1177/10668969241266925
Abstrakt:	The primordial odontogenic tumor (POT) is a rare mixed odontogenic tumor composed of mesenchymal cells, columnar odontogenic epithelium, and fibromyxoid stroma affecting the posterior mandible of children and adolescents. Herein, we report 3 patients with POT and the clinicopathological features of POT previously reported in the literature. A 12-year-old, 19-year-old, and 4-year-old patient presented an asymptomatic swelling in the posterior maxilla and posterior mandible. Imaging exams revealed radiolucent lesions associated with unerupted teeth. The lesions were surgically removed, and the histopathological examination revealed spindle-to-ovoid mesenchymal cells in a fibromyxoid stroma surfaced by columnar odontogenic epithelial cells with reverse nuclear polarization. Deposition of mineralized tissue was observed. The final diagnosis was POT, and patients did not exhibit signs of recurrence. POT should be included in the differential diagnoses of intraosseous lesions in the posterior mandible in pediatric patients. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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