Assessment of the Corneal Biomechanical Features of Sturge-Weber Syndrome Using Dynamic Ultrahigh-speed Scheimpflug Imaging.

Autor:	Xie M; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, Sichuan, China.; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing, China., Tang J; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China., Zhang Y; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.; West China School of Medicine, Sichuan University, Chengdu, Sichuan, China., Deng Y; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China., Ma K; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China., Xiang X; School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China; and.; Georgia State University, Atlanta, GA., Tang L; Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.
Jazyk:	angličtina
Zdroj:	Cornea [Cornea] 2024 Nov 01; Vol. 43 (11), pp. 1340-1347. Date of Electronic Publication: 2024 Sep 10.
DOI:	10.1097/ICO.0000000000003617
Abstrakt:	Purpose: To evaluate the corneal biomechanical characteristics of eyes with Sturge-Weber syndrome (SWS) secondary glaucoma (SSG) by analyzing corneal biomechanical parameters obtained using the Corneal Visualization Scheimpflug Technology instrument (Corvis ST). Methods: In patients with SWS, eyes affected by SSG were designated as the SSG group while the contralateral eyes were designated as the SWS contralateral group (SC group). Patients from the myopia clinic served as the control group. Dynamic corneal response parameters (DCRs) including the stress-strain index (SSI)-a critical material stiffness parameter that excludes interference from IOP and central corneal thickness (CCT)-were analyzed. Results: For CCT, no significant difference was observed between the SSG and SC groups. However, significant differences were found between the SSG and control groups and between the SC and control groups. Parameters such as HC Time, A1 Deformation Amp., A2 Deformation Amp., length of Whole Eye Movement (WEM), DA Ratio Max (2 mm), PachySlope, DA Ratio Max (1 mm), and ARTh showed significant differences between the SSG group and control group. In the SSG group, 4 of night eyes had an SSI of less than 0.85. Conclusions: Some DCRs indicated a stiffer cornea in the SSG group, possibly due to a thicker cornea in this group. On analyzing SSI, it was found that corneal material properties change, becoming less stiff in some of the patients with SSG. In conclusion, our study provides a preliminary exploration of the biomechanical properties of SWS secondary glaucoma. Competing Interests: All authors declare no conflict of interest. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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