Spider and scorpion knottins targeting voltage-gated sodium ion channels in pain signaling.
Autor: | Wang X; College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, Hunan 410128, China., Luo H; College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, Hunan 410128, China., Peng X; School of Public Health & Laboratory Medicine, Hunan University of Medicine, Huaihua 418000, China. Electronic address: peng112112@163.com., Chen J; College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, Hunan 410128, China; Hunan Provincial Engineering Technology Research Center for Cell Mechanics and Function Analysis, Changsha 418000, China. Electronic address: jinjunchen@hunau.edu.cn. |
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Jazyk: | angličtina |
Zdroj: | Biochemical pharmacology [Biochem Pharmacol] 2024 Sep; Vol. 227, pp. 116465. Date of Electronic Publication: 2024 Aug 03. |
DOI: | 10.1016/j.bcp.2024.116465 |
Abstrakt: | In sensory neurons that transmit pain signals, whether acute or chronic, voltage-gated sodium channels (VGSCs) are crucial for regulating excitability. Na Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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