A Comprehensive Review of Donor Corneal Preservation Strategies.
| Autor: | Cipolla J; University of Miami Miller School of Medicine, Miami, FL., Jo M; University of Tennessee College of Medicine, Memphis, TN; and., Sabater AL; University of Miami Miller School of Medicine, Miami, FL.; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL. |
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| Jazyk: | angličtina |
| Zdroj: | Cornea [Cornea] 2024 Nov 01; Vol. 43 (11), pp. 1456-1465. Date of Electronic Publication: 2024 Aug 02. |
| DOI: | 10.1097/ICO.0000000000003655 |
| Abstrakt: | Abstract: Successful corneal transplantation relies on the viability of the corneal endothelium. Although various preservation systems have been developed in the field of eye banking, long-term storage of the corneal endothelium poses challenges and is costly. Optisol-GS in the past has been the most commonly used solution for intermediate-term corneal storage in the United States. However, disruptions in the availability of Optisol-GS, caused by rising costs and supply shortages, have necessitated alternative methods of corneal preservation. Previously described preservation methods include hypothermia (2-8°C) for short-term storage (7-14 days), organ culture (28-37°C) for intermediate storage (4-7 weeks), and cryopreservation for longer-term storage. In this review, we examine standard practice and alternative methods for corneal storage. Competing Interests: A. L. Sabater: Ocubio, Tissuecor, Abbvie, Brill Pharma, GSK. J. Cipolla and M. Jo have no conflicts of interest to disclose. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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