An Unusual Presentation of Multiple Sclerotic Bone Lesions in Unicentric Castleman's Disease.

Autor: Balapanga S; Surgical Oncology, All India Institute of Medical Sciences, Mangalagiri, IND., Kalyan Kumar Reddy A; Internal Medicine, Sri Venkateswara Medical College, Tirupati, IND., D J S; Surgical Oncology, Cauvery Heart and Multispecialty Hospital, Mysuru, IND., Thirupathi MSV; Surgery, Sri Venkateswara Medical College, Tirupati, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Jul 03; Vol. 16 (7), pp. e63738. Date of Electronic Publication: 2024 Jul 03 (Print Publication: 2024).
DOI: 10.7759/cureus.63738
Abstrakt: Castleman's disease is a rare lymphoproliferative disease that usually presents as a solitary mass in the mediastinal or cervical region. Castleman's disease can be usually of two types: unicentric type (which involves only one site of lymph nodes) and multicentric type (which involves multiple sites of lymph nodes). We report the case of a 26-year-old female with multiple sclerotic bone lesions in unicentric Castleman's disease. The definitive diagnosis was made by excisional biopsy with immunohistochemistry, 18F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) study, and MRI scan. This case report emphasizes the need for proper workup for systemic manifestations in unicentric Castleman's disease.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Balapanga et al.)
Databáze: MEDLINE