Bilateral Blistering Rash Following Gastric Bypass Procedure and Mushroom Soup Diet: Hepatitis C Virus-Seronegative Necrolytic Acral Erythema.

Autor:	Smith LR; Department of Dermatology and Cutaneous Surgery, University of South Florida Morsani College of Medicine, Tampa, USA., Moore S; Department of Dermatology and Cutaneous Surgery, University of South Florida Morsani College of Medicine, Tampa, USA., Cardon B; Department of Dermatology and Cutaneous Surgery, University of South Florida Morsani College of Medicine, Tampa, USA., Gaudi S; Department of Pathology and Laboratory Medicine, James A. Haley Veterans' Hospital, Tampa, USA., Baldwin BT; Department of Dermatology, James A. Haley Veterans' Hospital, Tampa, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jul 03; Vol. 16 (7), pp. e63755. Date of Electronic Publication: 2024 Jul 03 (Print Publication: 2024).
DOI:	10.7759/cureus.63755
Abstrakt:	Necrolytic acral erythema (NAE) is an uncommon cutaneous disorder characterized by a symmetric acral distribution of erythematous plaques with underlying epidermal necrosis. While typically presenting in the context of hepatitis C virus (HCV) infection, NAE can also present secondary to nutritional deficiency or systemic disease. We present a case of NAE in a 66-year-old patient with no history of HCV infection status post gastric bypass who had a three-month history of eating only mushroom soup. The patient underwent a punch biopsy and was tested for a variety of nutritional deficiencies. Biopsy demonstrated partial necrosis of the upper epidermis, with subjacent re-epithelialization, squamatization, and vacuolopathy of the basal epidermis. He was treated with zinc replacement therapy after initial trials of tacrolimus and clobetasol were unsuccessful. At follow-up, he had significant improvement of the lesions. This case provides an example of an atypical presentation of NAE in the absence of HCV infection that presented as a complication of gastric bypass-associated nutritional deficiency. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Smith et al.)
Databáze:	MEDLINE
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