An Analysis of Drug-Related Problems in the Neurology Ward of a Tertiary Teaching Hospital: A Cross-Sectional Study.

Autor:	Borges M; Department of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto, BRA., Vilela Rodrigues JP; Department of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto, BRA., Freato Gonçalves AM; Department of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto, Brazil., Silveira Almeida Campos M; Department of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto, BRA., Rossi Varallo F; Department of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto, BRA., Barbosa Zanetti MO; Department of Psychiatric Nursing and Human Sciences, University of São Paulo, Ribeirão Preto, BRA., Regis Leira Pereira L; Department of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto, BRA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Jul 04; Vol. 16 (7), pp. e63829. Date of Electronic Publication: 2024 Jul 04 (Print Publication: 2024).
DOI:	10.7759/cureus.63829
Abstrakt:	Background and objective Drugs that act on the central nervous system have a high potential to cause drug-related problems (DRPs). A clinical pharmacist aided by collaborative efforts within an interdisciplinary healthcare team can prevent, detect, and resolve DRPs, thereby contributing to the promotion of medication safety and improving the quality of life of individuals under care. This study aimed to assess DRPs identified in the neurology ward of a tertiary hospital from February 2016 to November 2019. Methods This was a descriptive study with a cross-sectional and retrospective design involving secondary data collected from pharmaceutical care (PC) records. Student's t-tests, Pearson correlation coefficients, Poisson models, and logistic regression models were used to analyze the associations between age, number and type of medications, duration of hospitalization, and the occurrence of DRPs. Results A total of 130 patients were included in the study, and a total of 266 DRPs were detected, with 93 patients experiencing more than one DRP and 37 not presenting any DRPs. Necessity-related DRPs were the most prevalent (46.6%) type, followed by safety-related DRPs (28.6%). The prevalence of safety-related DRPs was higher in individuals older than 60 years (p<0.001). Conclusions Of note, 84.6% of the interventions suggested by pharmacists to resolve DRPs were accepted by the healthcare team. The high number of DRPs found underscores the importance of the clinical role of the pharmacist and interprofessional collaboration in the care of neurological patients, especially in the pharmaceutical follow-up of elderly individuals. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Research Ethics Committee of the Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, University of São Paulo issued approval CAAE (Certificate of Presentation for Ethical Appreciation): 29175414.8.0000.5440. All included patients signed the informed consent form. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Borges et al.)
Databáze:	MEDLINE
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