Non-ST Elevation Myocardial Infarction in Patients With Hypertensive Emergency.

Autor: Prakash GT; Department of Cardiology, E. S. Hospital, Villupuram, IND., Dhewle P; Department of Cardiology, Shrikrishna Hrudayalaya Hospital, Nagpur, IND., Bose SC; Department of Cardiology, Government Medical College, Ananthapuramu, IND., Kandibendla V; Department of Cardiology, Prakriya Hospitals, Nagasandra, IND.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Jul 03; Vol. 16 (7), pp. e63783. Date of Electronic Publication: 2024 Jul 03 (Print Publication: 2024).
DOI: 10.7759/cureus.63783
Abstrakt: Background Hypertensive emergencies represent high-cardiovascular-risk situations defined by severe increases in blood pressure. The prevalence of hypertension in non-ST elevation myocardial infarction (NSTEMI) is higher compared to STEMI and there is a lack of studies on NSTEMI patients with hypertensive emergencies. Patients with diabetes exhibited a higher rate of hypertensive emergencies. This study's primary aim was to investigate the coronary artery disease profile in hypertensive emergency patients with NSTEMI, and the secondary aim was to determine the impact of diabetes on the development of hypertensive emergencies. Methodology A total of 100 patients with NSTEMI and hypertensive emergency presenting to the hospital were enrolled in the study. The duration of the study was 24 months. The patients were also sub-grouped into diabetic and nondiabetic. Baseline characteristics were noted, and coronary angiogram and renal angiogram were also done. Based on variables, the chi-square test and t-test were employed to assess the significance. P -value < 0.05 was considered statistically significant. Results The mean age at presentation for patients with NSTEMI and hypertensive emergency was 58 years. Patients consuming alcohol were slightly higher (28, 28%) than those who smoked (23, 23%). Among all, 48 (48%) patients had diabetes. When considering the number of vessels, diabetic patients had more single-vessel diseases (18, 37.5%) and nondiabetic patients had more double-vessel diseases (15, 28.8%). The mean ejection fraction of the diabetic group was 56.1% ± 6.8% and the nondiabetic group was 54.2% ± 7.7%. Among all the patients, 52 (62.6%) used combination drugs, while 39 (46.9%) were on defaulter drugs. Conclusions Several risk factors like age, smoking, alcohol, and nonadherence to drugs were found to have an association with the occurrence of hypertensive emergency. Diabetes was found to be significantly associated with unfavorable coronary anatomy among the population.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. The Institutional Ethics Committee of Sri Jaydeva Institute of Cardiovascular Sciences issued approval IRB/SJICS/0753. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Prakash et al.)
Databáze: MEDLINE