Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration.

Autor:	Traidl-Hoffmann C; Institute of Environmental Medicine and Integrative Health, Faculty of Medicine, University of Augsburg, Augsburg, Germany.; Institute of Environmental Medicine, Helmholtz Zentrum München, Augsburg, Germany.; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland., Afghani J; Institute of Environmental Medicine and Integrative Health, Faculty of Medicine, University of Augsburg, Augsburg, Germany., Akdis CA; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Zurich, Switzerland., Akdis M; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Zurich, Switzerland., Aydin H; AbbVie Inc., North Chicago, Illinois, USA., Bärenfaller K; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Zurich, Switzerland., Behrendt H; Center for Allergy and Environment (ZAUM), Technische Universität München, Germany., Bieber T; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Davos Biosciences, Davos, Switzerland., Bigliardi P; University of Minnesota, Minneapolis, Minnesota, USA., Bigliardi-Qi M; University of Minnesota, Minneapolis, Minnesota, USA., Bonefeld CM; Department of Immunology and Microbiology, The LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark., Bösch S; Department of Dermatology, Allergy Unit, University Hospital of Zürich, Zürich, Switzerland.; Faculty of Medicine, University of Zürich, Zürich, Switzerland., Brüggen MC; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Department of Dermatology, Allergy Unit, University Hospital of Zürich, Zürich, Switzerland.; Faculty of Medicine, University of Zürich, Zürich, Switzerland., Diemert S; Almirall Hermal GmbH, Reinbek, Germany., Duchna HW; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Hochgebirgsklinik Davos, Davos, Switzerland., Fähndrich M; LEO Pharmaceutical Products Sarath Ltd, Zürich, Switzerland., Fehr D; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Department of Dermatology, Allergy Unit, University Hospital of Zürich, Zürich, Switzerland.; Faculty of Medicine, University of Zürich, Zürich, Switzerland., Fellmann M; Pfizer Switzerland AG, Zürich, Switzerland., Frei R; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Department of Pediatrics, Division of Respiratory Medicine and Allergology, Bern University Hospital, Bern, Switzerland.; Department of BioMedical Research (DBMR), University of Bern, Bern, Switzerland., Garvey LH; Department of Dermatology and Allergy, Allergy Clinic, Copenhagen University Hospital-Herlev and Gentofte, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Gharbo R; Psychosomatic Department, Hochgebirgsklinik, Davos, Switzerland., Gökkaya M; Institute of Environmental Medicine and Integrative Health, Faculty of Medicine, University of Augsburg, Augsburg, Germany.; Institute of Environmental Medicine, Helmholtz Zentrum München, Augsburg, Germany., Grando K; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Department of Dermatology, Allergy Unit, University Hospital of Zürich, Zürich, Switzerland.; Faculty of Medicine, University of Zürich, Zürich, Switzerland., Guillet C; Department of Dermatology, Allergy Unit, University Hospital of Zürich, Zürich, Switzerland.; Faculty of Medicine, University of Zürich, Zürich, Switzerland., Guler E; Pfizer, Istanbul, Turkey., Gutermuth J; Universitair Ziekenhuis, Brussel, Belgium., Herrmann N; Department of Dermatology and Allergy, University Hospital Bonn, Bonn, Germany., Hijnen DJ; Diakonessenhuis Utrecht Zeist Doorn Locatie Utrecht, Erasmus MC, University Medical Center Utrecht, Utrecht, Netherlands., Hülpüsch C; Institute of Environmental Medicine and Integrative Health, Faculty of Medicine, University of Augsburg, Augsburg, Germany.; Institute of Environmental Medicine, Helmholtz Zentrum München, Augsburg, Germany.; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland., Irvine AD; Department of Clinical Medicine, Trinity College Dublin, Dublin, Ireland., Jensen-Jarolim E; Center of Pathophysiology, Infectiology and Immunology, Institute of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria.; The interuniversity Messerli Research Institute, University of Veterinary Medicine Vienna, Medical University Vienna and University Vienna, Vienna, Austria., Kong HH; Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA., Koren H; Environmental Health, LLC, Durham, North Carolina, USA., Lang CCV; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Department of Immunology and Microbiology, The LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark.; Department of Dermatology, Allergy Unit, University Hospital of Zürich, Zürich, Switzerland., Lauener R; Ostschweizer Kinderspital St. Gallen, St.Gallen, Switzerland., Maintz L; Department of Dermatology and Allergy, University Hospital Bonn, Bonn, Germany., Mantel PY; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland., Maverakis E; Department of Dermatology, University of California Davis, Sacramento, California, USA., Möhrenschlager M; Hochgebirgsklinik Davos, Davos, Switzerland., Müller S; Department of Dermatology and Allergy, University Hospital Bonn, Bonn, Germany., Nadeau K; Stanford University School of Medicine, Stanford, California, USA., Neumann AU; Institute of Environmental Medicine and Integrative Health, Faculty of Medicine, University of Augsburg, Augsburg, Germany.; Institute of Environmental Medicine, Helmholtz Zentrum München, Augsburg, Germany., O'Mahony L; APC Microbiome Ireland, University College Cork, Cork, Ireland.; Department of Medicine and School of Microbiology, University College Cork, Cork, Ireland., Rabenja FR; Faculty of Médicine, Antananarivo, Madagascar., Renz H; Institute of Laboratory Medicine, Philipps University, Marburg, Germany., Rhyner C; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland., Rietschel E; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland., Ring J; Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technische Universität München, Munich, Germany., Roduit C; Department of Pediatrics, Division of Respiratory Medicine and Allergology, Bern University Hospital, Bern, Switzerland.; Ostschweizer Kinderspital St. Gallen, St.Gallen, Switzerland., Sasaki M; Department of Pediatrics, Division of Respiratory Medicine and Allergology, Bern University Hospital, Bern, Switzerland., Schenk M; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland., Schröder J; Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Schleswig-Holstein (UK-SH), Kiel, Germany., Simon D; Department of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Simon HU; Institute of Pharmacology, University of Bern, Bern, Switzerland.; Institute of Biochemistry, Brandenburg Medical School, Neuruppin, Germany., Sokolowska M; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Zurich, Switzerland., Ständer S; Center for Chronic Pruritus and Department of Dermatology, University Hospital Münster, Münster, Germany., Steinhoff M; Department of Dermatology and Venereology, Hamad Medical Corporation, Doha, Qatar.; Translational Research Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.; Dermatology Institute, Academic Health System, Hamad Medical Corporation, Doha, Qatar.; School of Medicine, Weill Cornell Medicine-Qatar, Ar-Rayyan, Qatar.; College of Medicine, Qatar University, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.; Department of Dermatology, Weill Cornell Medicine, New York, New York, USA., Piccirillo DS; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland., Taïeb A; INSERM 1312, University of Bordeaux, Bordeaux, France., Takaoka R; Department of Dermatology, Faculdade de Medicina, Hospital das Clínicas, Universidade de São Paulo, São Paulo, São Paulo, Brazil., Tapparo M; Bencard Allergie GmbH München, Munich, Germany., Teixeira H; Universitair Ziekenhuis, Brussel, Belgium., Thyssen JP; Department of Dermatology and Venerology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark., Traidl S; Department of Dermatology and Allergy, Hannover Medical School, Hannover, Germany.; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany., Uhlmann M; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland., van de Veen W; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Zurich, Switzerland., van Hage M; Department of Medicine Solna, Division of Immunology and Allergy, Karolinska Institute and Karolinska University Hospital Stockholm, Solna, Sweden., Virchow C; Department of Pneumology, Intensive Care Medicine, Center for Internal Medicine, Universitätsmedizin Rostock, Rostock, Germany., Wollenberg A; Department of Dermatology and Allergy, Ludwig-Maximilian-University, Munich, Germany.; Department of Dermatology and Allergy, University Hospital Augsburg, Augsburg, Germany.; Comprehensive Center of Inflammation Medicine, University Hospital Schleswig Holstein Campus Luebeck, Lubeck, Germany., Yasutaka M; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Zurich, Switzerland., Zink A; Department of Dermatology and Allergy, School of Medicine, Technical University of Munich, Munich, Germany.; Department of Medicine Solna, Division of Dermatology and Venereology, Karolinska Institutet, Stockholm, Sweden., Schmid-Grendelmeier P; Christine Kühne-Center for Allergy Research and Education (CK-CARE), Medicine Campus, Davos, Switzerland.; Department of Immunology and Microbiology, The LEO Foundation Skin Immunology Research Center, University of Copenhagen, Copenhagen, Denmark.; Department of Dermatology, Allergy Unit, University Hospital of Zürich, Zürich, Switzerland.
Jazyk:	angličtina
Zdroj:	Allergy [Allergy] 2024 Oct; Vol. 79 (10), pp. 2605-2624. Date of Electronic Publication: 2024 Aug 04.
DOI:	10.1111/all.16247
Abstrakt:	The 4th Davos Declaration was developed during the Global Allergy Forum in Davos which aimed to elevate the care of patients with atopic dermatitis (AD) by uniting experts and stakeholders. The forum addressed the high prevalence of AD, with a strategic focus on advancing research, treatment, and management to meet the evolving challenges in the field. This multidisciplinary forum brought together top leaders from research, clinical practice, policy, and patient advocacy to discuss the critical aspects of AD, including neuroimmunology, environmental factors, comorbidities, and breakthroughs in prevention, diagnosis, and treatment. The discussions were geared towards fostering a collaborative approach to integrate these advancements into practical, patient-centric care. The forum underlined the mounting burden of AD, attributing it to significant environmental and lifestyle changes. It acknowledged the progress in understanding AD and in developing targeted therapies but recognized a gap in translating these innovations into clinical practice. Emphasis was placed on the need for enhanced awareness, education, and stakeholder engagement to address this gap effectively and to consider environmental and lifestyle factors in a comprehensive disease management strategy. The 4th Davos Declaration marks a significant milestone in the journey to improve care for people with AD. By promoting a holistic approach that combines research, education, and clinical application, the Forum sets a roadmap for stakeholders to collaborate to improve patient outcomes in AD, reflecting a commitment to adapt and respond to the dynamic challenges of AD in a changing world. (© 2024 The Author(s). Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.)
Databáze:	MEDLINE
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