High precision blood lead radiogenic isotope signatures in a community exposed to Pb contaminated soils and implications for the current Pb exposure of the European population.

Autor: Petit JCJ; Institut Scientifique de Service Public, Rue du Chéra 200, 4000 Liège, Belgium. Electronic address: j.petit@issep.be., Mattielli N; Laboratoire G-TIME, Faculté des Sciences, Université Libre de Bruxelles, Av. F.D. Roosevelt 50 CP106/02 1050, Bruxelles, Belgium., De Jong J; Laboratoire G-TIME, Faculté des Sciences, Université Libre de Bruxelles, Av. F.D. Roosevelt 50 CP106/02 1050, Bruxelles, Belgium., Bouhoulle E; Institut Scientifique de Service Public, Rue du Chéra 200, 4000 Liège, Belgium., Debouge W; Laboratoire G-TIME, Faculté des Sciences, Université Libre de Bruxelles, Av. F.D. Roosevelt 50 CP106/02 1050, Bruxelles, Belgium., Maggi P; FPS Health, Food Chain Safety and Environment, Ecotoxicology Unit from Service Plant protection and Fertilising products, 5/2 Avenue Galilée, B-1210 Brussels, Belgium., Hublet G; Laboratoire G-TIME, Faculté des Sciences, Université Libre de Bruxelles, Av. F.D. Roosevelt 50 CP106/02 1050, Bruxelles, Belgium., Fagel N; Laboratoire Argiles, Géochimie et Environnements sédimentaires (AGEs), Department of Geology, Faculty of Sciences, University of Liège, Liège B-4000, Belgium., Pirard C; Laboratory of Clinical, Forensic and Environmental Toxicology, CHU of Liege, B35, B-4000 Liege, Belgium., Charlier C; Laboratory of Clinical, Forensic and Environmental Toxicology, CHU of Liege, B35, B-4000 Liege, Belgium., Suzanne R; Institut Scientifique de Service Public, Rue du Chéra 200, 4000 Liège, Belgium.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2024 Nov 10; Vol. 950, pp. 174763. Date of Electronic Publication: 2024 Aug 02.
DOI: 10.1016/j.scitotenv.2024.174763
Abstrakt: Our study provides the most comprehensive dataset for high-precision radiogenic isotopes of lead (Pb) in blood for the western European population. It investigates their potential for elucidating the contribution of soil Pb to blood Pb using a human biomonitoring survey involving 81 adults and 4 children living in the urban area of Liège (Belgium). Soils in the area show moderate (median of 360 mg/kg) to high (95th percentile of 1000 mg/kg) Pb concentrations, due to former metal processing activities. Blood lead levels (BLL) measured in the study population are, on average, quantitatively consistent with a ∼ 20 % increase due to the exposure to Pb from soils, as estimated by a single-compartment biokinetic model. Consistently, its isotopic composition does not represent an endmember that fully accounts for the variability of Blood lead isotope (BLI) compositions measured in the study population. While some individuals show more thorogenic BLI ratios (relatively more enriched in 208 Pb), which could be consistent with a greater exposure to local soils and/or by their country of birth, the BLI data mostly follow a trend roughly parallel to the European Standard Lead Pollution (ESLP) line, within the European leaded gasoline field, even two decades after the withdrawal of this source. Differences in BLI are probably associated with factors related to the presence of Pb in dwellings (pipes, paint) and drinking water distribution system, suggesting that the anthropogenic Pb in use, relevant to human exposure, may contain ore components of different origins, including the Australian Pb ore signature.
Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Petit reports financial support was provided by Walloon Public Service. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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