Methodological Considerations in Evaluating Breast Cancer Screening Studies.

Autor:	Narayan AK; University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Miles RC; Department of Radiology, Denver Health, Denver, CO, USA., Woods RW; University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA., Spalluto LB; Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Burnside ES; University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Jazyk:	angličtina
Zdroj:	Journal of breast imaging [J Breast Imaging] 2024 Nov 05; Vol. 6 (6), pp. 577-585.
DOI:	10.1093/jbi/wbae038
Abstrakt:	In evidence-based medicine frameworks, the highest level of evidence is derived from quantitative synthesis of double-masked, high-quality, randomly assigned controlled trials. Meta-analyses of randomly assigned controlled trials have demonstrated that screening mammography reduces breast cancer deaths. In the United States, every major guideline-producing organization has recommended screening mammography in average-risk women; however, there are controversies about age and frequency. Carefully controlled observational research studies and statistical modeling studies can address evidence gaps and inform evidence-based, contemporary screening practices. As breast imaging radiologists develop and evaluate existing and new screening tests and technologies, they will need to understand the key methodological considerations and scientific criteria used by policy makers and health service researchers to support dissemination and implementation of evidence-based screening tests. The Wilson and Jungner principles and the U.S. Preventive Services Task Force general analytic framework provide structured evaluations of the effectiveness of screening tests. Key considerations in both frameworks include public health significance, natural history of disease, cost-effectiveness, and characteristics of screening tests and treatments. Rigorous evaluation of screening tests using analytic frameworks can maximize the benefits of screening tests while reducing potential harms. The purpose of this article is to review key methodological considerations and analytic frameworks used to evaluate screening studies and develop evidence-based recommendations. (© Society of Breast Imaging 2024. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
Databáze:	MEDLINE
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