Antimicrobial activity, foaming properties, and interacting mechanism of rhamnolipids in presence of silk fibroin through spectroscopy, molecular docking, and microbiological experiments.

Autor: Li Y; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, PR China., Guo Y; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, PR China., Jiang H; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, PR China., Zhang Q; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, PR China. Electronic address: zhangqianlcu@163.com., Liu J; School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, Shandong 252059, PR China. Electronic address: liujielcu@126.com.
Jazyk: angličtina
Zdroj: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2024 Dec 15; Vol. 323, pp. 124899. Date of Electronic Publication: 2024 Jul 29.
DOI: 10.1016/j.saa.2024.124899
Abstrakt: As a type of biosurfactant, rhamnolipids (RLs) are multifunctional skin-care ingredients, and the molecular interaction of RLs with silk fibroin (SF) is a more complicated process than has long been believed. The interaction and functional properties of them, and their potential as fungicidal agents for agricultural products and as organic preservatives for cosmetics were assessed in this paper. The SF addition makes the RLs aggregation easier through the complexes formation, which decreases the applied concentration of surfactant. The results of spectroscopic analyses and molecular docking suggest that hydrogen bonding and van der Waals forces are significant contributed to the binding mechanism between the two substances. The addition of SF notably enhances the foaming capacity and stability of RLs. The certain antibacterial and antifungal properties of RLs are basically not affected by the SF addition, even the SF-RLS system demonstrates an unobvious synergistic inhibitory impact on Glomerella cingulate (GC). The results offer a theoretical framework for the utilization of RLs as natural fungicides and preservatives in presence of nutritional components, considering the properties of RLs as nontoxic, biodegradable, environmentally friendly, and good compatibility.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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