A case report of interstitial pneumonia induced by vedolizumab in a patient with ulcerative colitis.
| Autor: | Liu A; Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China., Ye S; Liver Disease Center, The Affiliated Hospital of Qingdao University, Qingdao, China., Diao Z; Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China., Liu H; Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China., Xu Y; Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China., Wu J; Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China., Mao T; Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China., Tian Z; Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China., Ding X; Department of Gastroenterology, the Affiliated Hospital of Qingdao University, Qingdao, China. |
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| Jazyk: | angličtina |
| Zdroj: | Medicine [Medicine (Baltimore)] 2024 Aug 02; Vol. 103 (31), pp. e39195. |
| DOI: | 10.1097/MD.0000000000039195 |
| Abstrakt: | Rationale: The interstitial pneumonia (IP) linked to vedolizumab (VDZ) in patients with ulcerative colitis (UC) is rare. Prompt diagnosis and treatment can improve patient outcomes. Patient Concerns: A 39-year-old man with UC who received VDZ as sole therapy developed symptoms such as chest tightness, cough, and suffocation. Diagnoses: IP was confirmed through pulmonary function tests, chest computed tomography, and bronchoscopic biopsy. Interventions: The patient was given methylprednisolone and VDZ cessation. Outcomes: The patient's symptoms improved and remained symptom-free after nearly 2 years. Lessons: VDZ-induced IP should be considered when evaluating pulmonary infections in UC patients treated with VDZ. Competing Interests: The authors have no conflicts of interest to disclose. (Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.) |
| Databáze: | MEDLINE |
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